» Articles » PMID: 23307579

Recent Developments in Diagnosis and Assessment of Morphea

Overview
Publisher Current Science
Specialty Rheumatology
Date 2013 Jan 12
PMID 23307579
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

There is huge variation in the evaluation, diagnosis, and treatment of patients with morphea (localized scleroderma). In part, this variability results from the lack of validated methods to assess severity and outcomes with a consequent lack of adequate therapeutic trials. Evaluation is also hindered by lack of information regarding the impact of morphea on patients. Recent studies are addressing this gap in knowledge and include: development of clinical outcome measures, validation of imaging studies, publication of consensus treatment plans, and increased understanding of the impact of morphea on patients and parents. The purpose of this review is to summarize the results of these studies and to synthesize the information into a rational approach to the diagnosis and assessment of patients with morphea.

Citing Articles

High-frequency ultrasound evaluation of morphea: Retrospective analytical study.

Yazdanparast T, Mohseni A, Dehghan K, Delavar S, Firooz A Skin Res Technol. 2024; 30(7):e13818.

PMID: 38924131 PMC: 11197076. DOI: 10.1111/srt.13818.


Role of imaging in morphea assessment: A review of the literature.

Khorasanizadeh F, Kalantari Y, Etesami I Skin Res Technol. 2023; 29(7):e13410.

PMID: 37522502 PMC: 10318382. DOI: 10.1111/srt.13410.


Study about evaluation of efficacy of methotrexate in localized scleroderma using ultrasonography.

Zhang F, Li J, Zhao Q, Liu H, Zhang F Skin Res Technol. 2023; 29(3):e13300.

PMID: 36973989 PMC: 10155795. DOI: 10.1111/srt.13300.


Morphea: The 2023 update.

Papara C, De Luca D, Bieber K, Vorobyev A, Ludwig R Front Med (Lausanne). 2023; 10:1108623.

PMID: 36860340 PMC: 9969991. DOI: 10.3389/fmed.2023.1108623.


Controversy around the morphea.

Danczak-Pazdrowska A, Cieplewicz P, Zaba R, Adamski Z, Polanska A Postepy Dermatol Alergol. 2021; 38(5):716-720.

PMID: 34849114 PMC: 8610066. DOI: 10.5114/ada.2021.106242.


References
1.
Ennis H, Herrick A, Baildam E, Richards H . Childrens' and parents' beliefs about childhood onset scleroderma are influenced by child age and physical function impairment. Rheumatology (Oxford). 2012; 51(7):1331-3. DOI: 10.1093/rheumatology/kes071. View

2.
Skobieranda K, Helm K . Decreased expression of the human progenitor cell antigen (CD34) in morphea. Am J Dermatopathol. 1995; 17(5):471-5. DOI: 10.1097/00000372-199510000-00007. View

3.
Arkachaisri T, Vilaiyuk S, Li S, ONeil K, Pope E, Higgins G . The localized scleroderma skin severity index and physician global assessment of disease activity: a work in progress toward development of localized scleroderma outcome measures. J Rheumatol. 2009; 36(12):2819-29. PMC: 3690503. DOI: 10.3899/jrheum.081284. View

4.
Baildam E, Ennis H, Foster H, Shaw L, Chieng A, Kelly J . Influence of childhood scleroderma on physical function and quality of life. J Rheumatol. 2010; 38(1):167-73. DOI: 10.3899/jrheum.100447. View

5.
Li S, Torok K, Pope E, Dedeoglu F, Hong S, Jacobe H . Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. Arthritis Care Res (Hoboken). 2012; 64(8):1175-85. PMC: 3724335. DOI: 10.1002/acr.21687. View