Accelerated Image Reconstruction in Fluorescence Molecular Tomography Using Dimension Reduction

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2013 Jan 11

PMID 23304643

Citations 4

Authors

Xu Cao

Xin Wang

Bin Zhang

Fei Liu

Jianwen Luo

Jing Bai

Affiliations

Soon will be listed here.

Abstract

With the development of charge-coupled device (CCD) camera based non-contact fluorescence molecular tomography (FMT) imaging systems, multi projections and densely sampled fluorescent measurements used in subsequent image reconstruction can be easily obtained. However, challenges still remain in fast image reconstruction because of the large computational burden and memory requirement in the inverse problem. In this work, an accelerated image reconstruction method in FMT using principal components analysis (PCA) is presented to reduce the dimension of the inverse problem. Phantom experiments are performed to verify the feasibility of the proposed method. The results demonstrate that the proposed method can accelerate image reconstruction in FMT almost without quality degradation.

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