The Role of Radiotherapy and Chemotherapy in the Treatment of Primary Adult High Grade Gliomas: Assessment of Patients for These Treatment Approaches and the Common Immediate Side Effects
Overview
Affiliations
Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these conventional therapies, and in spite of treatment advances the prognosis remains poor.
Therapeutic effect of natural polyphenols against glioblastoma.
Beylerli O, Beilerli A, Shumadalova A, Wang X, Yang M, Sun H Front Cell Dev Biol. 2022; 10:1036809.
PMID: 36268515 PMC: 9577362. DOI: 10.3389/fcell.2022.1036809.
Rayan A, Abdel-Kareem S, Hasan H, Zahran A, Gamal D Rep Pract Oncol Radiother. 2020; 25(6):890-898.
PMID: 32982596 PMC: 7498706. DOI: 10.1016/j.rpor.2020.08.010.
Hu J, Hu J, Jiao H, Li Q Mol Med Rep. 2018; 18(1):184-192.
PMID: 29749446 PMC: 6059668. DOI: 10.3892/mmr.2018.8945.
Yang J, Zhang J, Chen W, Wang G, Mao Q, Li S Oncotarget. 2017; 8(24):38444-38455.
PMID: 28404978 PMC: 5503544. DOI: 10.18632/oncotarget.16461.
Lai Y, Chen M, Lin S, Lin S, Wong Y, Yu S Oncotarget. 2015; 6(28):26252-65.
PMID: 26312766 PMC: 4694899. DOI: 10.18632/oncotarget.4761.