Gender Differences in Drug Bioequivalence: Time to Rethink Practices

Overview

Journal Clin Pharmacol Ther

Publisher Wiley

Specialty Pharmacology

Date 2013 Jan 10

PMID 23299647

Citations 11

Authors

G Koren

H Nordeng

S MacLeod

Affiliations

Soon will be listed here.

Abstract

Currently, bioequivalence (BE) studies are carried out exclusively in males, assuming that intrasubject variabilities are similar between the sexes. This article challenges this hypothesis on the basis of available evidence and urges that studies of BE of sufficient power be undertaken in women also for all generic drugs aimed at women.

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