Diffusion Tensor Imaging and Fiber Tractography in Brain Malformations

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2013 Jan 5

PMID 23288476

Citations 27

Authors

Andrea Poretti

Avner Meoded

Andrea Rossi

Charles Raybaud

Thierry A G M Huisman

Affiliations

Soon will be listed here.

Abstract

Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and quantitative information about the micro-architecture of white matter. DTI and its post-processing tool fiber tractography (FT) have been increasingly used in the last decade to investigate the microstructural neuroarchitecture of brain malformations. This article aims to review the use of DTI and FT in the evaluation of a variety of common, well-described brain malformations, in particular by pointing out the additional information that DTI and FT renders compared with conventional MR sequences. In addition, the relevant existing literature is summarized.

Citing Articles

Acquisition and Analysis of Excised Neocortex from Pediatric Patients with Focal Cortical Dysplasia Using Mesoscale Diffusion MRI.

Fountain C, Ghuman H, Paldino M, Tamber M, Panigrahy A, Modo M Diagnostics (Basel). 2023; 13(9).

PMID: 37174921 PMC: 10177920. DOI: 10.3390/diagnostics13091529.

Challenges in the pre- and post-natal diagnosis of posterior fossa cysts: A case report and review of historical evolution of descriptive terminologies.

Kutty S, Clarke G, Kutty J Surg Neurol Int. 2022; 13:449.

PMID: 36324928 PMC: 9610524. DOI: 10.25259/SNI_602_2022.

Coordinating cerebral cortical construction and connectivity: Unifying influence of radial progenitors.

Casingal C, Descant K, Anton E Neuron. 2022; 110(7):1100-1115.

PMID: 35216663 PMC: 8989671. DOI: 10.1016/j.neuron.2022.01.034.

A Proposed Clinical Classification and a Diagnostic Approach for Congenital Ataxias.

Raslan I, Barsottini O, Pedroso J Neurol Clin Pract. 2021; 11(3):e328-e336.

PMID: 34484907 PMC: 8382376. DOI: 10.1212/CPJ.0000000000000966.

The role of preoperative diffusion tensor imaging in predicting and improving functional outcome in pediatric patients undergoing epilepsy surgery: a systematic review.

Leon-Rojas J, Cornell I, Rojas-Garcia A, DArco F, Panovska-Griffiths J, Cross H BJR Open. 2021; 3(1):20200002.

PMID: 34381942 PMC: 8320117. DOI: 10.1259/bjro.20200002.

References

Bomfim R, F Tavora D, Nakayama M, Gama R . Horizontal gaze palsy with progressive scoliosis: CT and MR findings. Pediatr Radiol. 2008; 39(2):184-7. DOI: 10.1007/s00247-008-1058-8. View

Hahn J, Plawner L . Evaluation and management of children with holoprosencephaly. Pediatr Neurol. 2004; 31(2):79-88. DOI: 10.1016/j.pediatrneurol.2004.03.006. View

Dill P, Poretti A, Boltshauser E, Huisman T . Fetal magnetic resonance imaging in midline malformations of the central nervous system and review of the literature. J Neuroradiol. 2009; 36(3):138-46. DOI: 10.1016/j.neurad.2008.12.001. View

Moog U, Jones M, Bird L, Dobyns W . Oculocerebrocutaneous syndrome: the brain malformation defines a core phenotype. J Med Genet. 2005; 42(12):913-21. PMC: 1735958. DOI: 10.1136/jmg.2005.031369. View

Alexiou G, Sfakianos G, Prodromou N . Dandy-Walker malformation: analysis of 19 cases. J Child Neurol. 2009; 25(2):188-91. DOI: 10.1177/0883073809338410. View

Dietrich R, Glidden D, ROTH G, Martin R, Demo D . The Proteus syndrome: CNS manifestations. AJNR Am J Neuroradiol. 1998; 19(5):987-90. PMC: 8337570. View

Haller S, Wetzel S, Lutschg J . Functional MRI, DTI and neurophysiology in horizontal gaze palsy with progressive scoliosis. Neuroradiology. 2008; 50(5):453-9. DOI: 10.1007/s00234-007-0359-1. View

Sang L, Miller J, Corbit K, Giles R, Brauer M, Otto E . Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011; 145(4):513-28. PMC: 3383065. DOI: 10.1016/j.cell.2011.04.019. View

Briguglio M, Pinelli L, Giordano L, Ferraris A, Germano E, Micheletti S . Pontine Tegmental Cap Dysplasia: developmental and cognitive outcome in three adolescent patients. Orphanet J Rare Dis. 2011; 6:36. PMC: 3123550. DOI: 10.1186/1750-1172-6-36. View

10.

Widjaja E, Mahmoodabadi S, Otsubo H, Snead O, Holowka S, Bells S . Subcortical alterations in tissue microstructure adjacent to focal cortical dysplasia: detection at diffusion-tensor MR imaging by using magnetoencephalographic dipole cluster localization. Radiology. 2009; 251(1):206-15. DOI: 10.1148/radiol.2511081092. View

11.

Toelle S, Yalcinkaya C, Kocer N, Deonna T, Overweg-Plandsoen W, Bast T . Rhombencephalosynapsis: clinical findings and neuroimaging in 9 children. Neuropediatrics. 2002; 33(4):209-14. DOI: 10.1055/s-2002-34498. View

12.

Utsunomiya H, Yamashita S, Takano K, Okazaki M . Arrangement of fiber tracts forming Probst bundle in complete callosal agenesis: report of two cases with an evaluation by diffusion tensor tractography. Acta Radiol. 2006; 47(10):1063-6. DOI: 10.1080/02841850600930025. View

13.

Sukhudyan B, Jaladyan V, Melikyan G, Schlump J, Boltshauser E, Poretti A . Gómez-López-Hernández syndrome: reappraisal of the diagnostic criteria. Eur J Pediatr. 2010; 169(12):1523-8. DOI: 10.1007/s00431-010-1259-7. View

14.

Poretti A, Singhi S, Huisman T, Meoded A, Jallo G, Ozturk A . Tecto-cerebellar dysraphism with occipital encephalocele: not a distinct disorder, but part of the Joubert syndrome spectrum?. Neuropediatrics. 2011; 42(4):170-4. DOI: 10.1055/s-0031-1287763. View

15.

Mercuri E, Messina S, Bruno C, Mora M, Pegoraro E, Comi G . Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population study. Neurology. 2009; 72(21):1802-9. DOI: 10.1212/01.wnl.0000346518.68110.60. View

16.

Yagishita A, Arai N, Tamagawa K, Oda M . Hemimegalencephaly: signal changes suggesting abnormal myelination on MRI. Neuroradiology. 1998; 40(11):734-8. DOI: 10.1007/s002340050674. View

17.

Mohanty A, Biswas A, Satish S, Praharaj S, Sastry K . Treatment options for Dandy-Walker malformation. J Neurosurg. 2007; 105(5 Suppl):348-56. DOI: 10.3171/ped.2006.105.5.348. View

18.

Simon E, Hevner R, Pinter J, Clegg N, Delgado M, Kinsman S . The dorsal cyst in holoprosencephaly and the role of the thalamus in its formation. Neuroradiology. 2001; 43(9):787-91. DOI: 10.1007/s002340100567. View

19.

Rollins N, Reyes T, Chia J . Diffusion tensor imaging in lissencephaly. AJNR Am J Neuroradiol. 2005; 26(6):1583-6. PMC: 8149082. View

20.

Juranek J, Salman M . Anomalous development of brain structure and function in spina bifida myelomeningocele. Dev Disabil Res Rev. 2010; 16(1):23-30. PMC: 2917986. DOI: 10.1002/ddrr.88. View