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A Single Dose Desensitization for Summer Hay Fever. Results of a Double Blind Study-1988

Overview
Specialty Pharmacology
Date 1990 Jan 1
PMID 2328752
Citations 4
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Abstract

A new type of desensitising vaccine, enzyme potentiated was subjected to a double-blind randomised study during the hay fever season. The vaccine is a convenient single injection given in March and the results show good protection throughout the grass pollen season.

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References
1.
. CSM Update: Desensitising vaccines. Br Med J (Clin Res Ed). 2010; 293(6552):948. PMC: 1341725. View

2.
Scadding G, Brostoff J . Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite. Clin Allergy. 1986; 16(5):483-91. DOI: 10.1111/j.1365-2222.1986.tb01983.x. View

3.
Ganderton M, Brostoff J, Frankland A . Comparison of preseasonal and coseasonal Allpyral with Depo-Medrone in summer hay-fever. Br Med J. 1969; 1(5640):357-8. PMC: 1982610. DOI: 10.1136/bmj.1.5640.357. View

4.
Freeman J . Further observations on the treatment of hay fever by hypodermic inoculations of pollen vaccine. Historical document. Ann Allergy. 1960; 18:427-34. View

5.
McEwen L, Starr M . Enzyme-potentiated hyposensitisation. I. The effect of pre-treatment with -glucuronidase, hyaluronidase, and antigen on anaphylactic sensitivity of guinea-pigs, rats and mice. Int Arch Allergy Appl Immunol. 1972; 42(1):152-8. View