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Low-cost Tools for Diagnosing and Monitoring HIV Infection in Low-resource Settings

Overview
Specialty Public Health
Date 2013 Jan 4
PMID 23284197
Citations 70
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Abstract

Low-cost technologies to diagnose and monitor human immunodeficiency virus (HIV) infection in developing countries are a major subject of current research and health care in the developing world. With the great need to increase access to affordable HIV monitoring services in rural areas of developing countries, much work has been focus on the development of point-of-care technologies that are affordable, robust, easy to use, portable and of sufficient quantitative accuracy to enable clinical decision-making. For diagnosis of HIV infection, some low-cost tests, such as lateral flow tests and enzyme-linked immunosorbent assays, are already in place and well established. However, portable quantitative tests for rapid HIV monitoring at the point of care have only recently been introduced to the market. In this review, we discuss low-cost tests for HIV diagnosis and monitoring in low-resource settings, including promising technologies for use at the point of care, that are available or close to market.

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References
1.
Tanriverdi S, Chen L, Chen S . A rapid and automated sample-to-result HIV load test for near-patient application. J Infect Dis. 2010; 201 Suppl 1:S52-8. DOI: 10.1086/650387. View

2.
Branson B . The future of HIV testing. J Acquir Immune Defic Syndr. 2011; 55 Suppl 2:S102-5. DOI: 10.1097/QAI.0b013e3181fbca44. View

3.
Mtapuri-Zinyowera S, Chideme M, Mangwanya D, Mugurungi O, Gudukeya S, Hatzold K . Evaluation of the PIMA point-of-care CD4 analyzer in VCT clinics in Zimbabwe. J Acquir Immune Defic Syndr. 2010; 55(1):1-7. DOI: 10.1097/QAI.0b013e3181e93071. View

4.
Stevens W, Scott L, Crowe S . Quantifying HIV for monitoring antiretroviral therapy in resource-poor settings. J Infect Dis. 2010; 201 Suppl 1:S16-26. DOI: 10.1086/650392. View

5.
Steegen K, Luchters S, De Cabooter N, Reynaerts J, Mandaliya K, Plum J . Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings. J Virol Methods. 2007; 146(1-2):178-87. DOI: 10.1016/j.jviromet.2007.06.019. View