Chest Pain and Exacerbations of Bronchiectasis

Overview

Journal Int J Gen Med

Publisher Dove Medical Press

Specialty General Medicine

Date 2012 Dec 29

PMID 23271921

Citations 1

Authors

Paul T King

Stephen R Holdsworth

Michael Farmer

Nicholas J Freezer

Peter W Holmes

Affiliations

Soon will be listed here.

Abstract

Background: Bronchiectasis is a common disease and a major cause of respiratory morbidity. Chest pain has been described as occurring in the context of bronchiectasis but has not been well characterized. This study was performed to describe the characteristics of chest pain in adult bronchiectasis and to define the relationship of this pain to exacerbations.

Subjects And Methods: We performed a prospective study of 178 patients who were followed-up for 8 years. Subjects were reviewed on a yearly basis and assessed for the presence of chest pain. Subjects who had chest pain at the time of clinical review by the investigators were included in this study. Forty-four patients (25%) described respiratory chest pain at the time of assessment; in the majority of cases 39/44 (89%), this occurred with an exacerbation and two distinct types of chest pain could be described: pleuritic (n = 4) and non-pleuritic (n = 37), with two subjects describing both forms. The non-pleuritic chest pain occurred most commonly over both lower lobes and was mild to moderate in severity. The pain subsided as patients recovered.

Conclusion: Non-pleuritic chest pain occurs in subjects with bronchiectasis generally in association with exacerbations.

Citing Articles

A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects.

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PMID: 36173685 PMC: 9746903. DOI: 10.1172/jci.insight.158378.

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