A Load of Small RNAs in the Sperm - How Many Bits of Hereditary Information?

Overview

Journal Cell Res

Specialty Cell Biology

Date 2012 Dec 26

PMID 23266892

Citations 12

Authors

Jafar Kiani

Minoo Rassoulzadegan

Affiliations

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Abstract

Transcriptionally silent sperm contains a variety of RNA fragments of both coding and non-coding transcripts. A recent article by Peng and colleagues reveals several new families of small RNAs enriched in sperm, which are derived from the same locus as tRNAs. The finding of these short fragments of tRNA in the sperm raises once again the question of the possible function(s) of such a miniaturized form of information carried by the spermatozoon.

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