Oral Nicotine Self-Administration in Rodents

Overview

Journal J Addict Res Ther

Date 2012 Dec 25

PMID 23264883

Citations 15

Authors

Allan C Collins

Sakire Pogun

Tanseli Nesil

Lutfiye Kanit

Affiliations

Soon will be listed here.

Abstract

Nicotine addiction is a complex process that begins with self-administration. Consequently, this process has been studied extensively using animal models. A person is usually not called "smoker" if s/he has smoked for a week or a month in a lifetime; in general, a smoker has been smoking for many years. Furthermore, a smoker has free access to cigarettes and can smoke whenever she/he wants, provided there are no social/legal restraints. Subsequently, in an animal model of tobacco addiction, it will be desirable to expose the animal to free access nicotine for 24 hours/day for many weeks, starting at different stages of development.

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