Neonatal Gastric Lactobezoar: Management with N-acetylcysteine

Overview

Journal Case Rep Pediatr

Publisher Wiley

Specialty Pediatrics

Date 2012 Dec 18

PMID 23243542

Citations 3

Authors

Sarah Bajorek

Roel Basaldua

Katherine McGoogan

Charla Miller

Craig B Sussman

Affiliations

Soon will be listed here.

Abstract

Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed.

Citing Articles

N-Acetylcysteine for Gastric Lactobezoars in a 1-Month-Old.

Savva D, Crist M, Lardieri A J Pediatr Pharmacol Ther. 2019; 24(3):247-250.

PMID: 31093026 PMC: 6510517. DOI: 10.5863/1551-6776-24.3.247.

Recurrent gastric lactobezoar in an infant.

Castro L, Berenguer A, Pilar C, Goncalves R, Nunes J Oxf Med Case Reports. 2015; 2014(4):80-2.

PMID: 25988036 PMC: 4399510. DOI: 10.1093/omcr/omu031.

Treatment of a gastric lactobezoar with N-acetylcysteine.

Sparks B, Kesavan A Case Rep Gastrointest Med. 2014; 2014:254741.

PMID: 25505999 PMC: 4258365. DOI: 10.1155/2014/254741.

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