A Family History Study of Neuropsychiatric Disorders in the Adult Siblings of Autistic Individuals

Overview

Journal J Am Acad Child Adolesc Psychiatry

Publisher Elsevier

Specialties Pediatrics
Psychiatry

Date 1990 Mar 1

PMID 2324058

Citations 46

Authors

J Piven

J Gayle

G A Chase

B Fink

R Landa

M M Wzorek

S E Folstein

Affiliations

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Abstract

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals.

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