Photoacoustic and Ultrasound Dual-modality Imaging of Human Peripheral Joints

Overview

Journal J Biomed Opt

Specialties Biomedical Engineering
Ophthalmology

Date 2012 Dec 14

PMID 23235916

Citations 28

Authors

Guan Xu

Justin R Rajian

Gandikota Girish

Mariana J Kaplan

J Brian Fowlkes

Paul L Carson

Xueding Wang

Affiliations

Soon will be listed here.

Abstract

A photoacoustic (PA) and ultrasound (US) dual modality system, for imaging human peripheral joints, is introduced. The system utilizes a commercial US unit for both US control imaging and PA signal acquisition. Preliminary in vivo evaluation of the system, on normal volunteers, revealed that this system can recover both the structural and functional information of intra- and extra-articular tissues. Confirmed by the control US images, the system, on the PA mode, can differentiate tendon from surrounding soft tissue based on the endogenous optical contrast. Presenting both morphological and pathological information in joint, this system holds promise for diagnosis and characterization of inflammatory joint diseases such as rheumatoid arthritis.

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