Biomarkers in Uterine Leiomyoma
Overview
Affiliations
Biomarkers are biologic compounds that are easily accessible and reflect normal physiology or pathology. They are useful in a variety of clinical situations that involve detection of subclinical disease, risk stratification, preoperative planning, and monitoring treatment. A useful intervention needs to exist for a biomarker to be an effective tool. Many compounds have been investigated as potential biomarkers for the diagnosis and surveillance of uterine leiomyomas. Most of these compounds demonstrate subtle differences among patients when leiomyomas are compared with controls. The compounds investigated lack the diagnostic accuracy necessary to add any benefit to the current available modalities used to diagnose and monitor uterine leiomyomas.
The Impact of Adenomyosis on Pregnancy.
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PMID: 39200389 PMC: 11351718. DOI: 10.3390/biomedicines12081925.
Karim S, Fattah C J Int Med Res. 2023; 51(4):3000605231158949.
PMID: 37013263 PMC: 10074628. DOI: 10.1177/03000605231158949.
PLP1 may serve as a potential diagnostic biomarker of uterine fibroids.
Cai L, Liao Z, Li S, Wu R, Li J, Ren F Front Genet. 2022; 13:1045395.
PMID: 36386836 PMC: 9662689. DOI: 10.3389/fgene.2022.1045395.
Benign metastasising leiomyoma: a rare disease and a diagnostic challenge.
Li M, Lee A, Wong W, Tan K BMJ Case Rep. 2022; 15(7).
PMID: 35835485 PMC: 9289031. DOI: 10.1136/bcr-2021-248575.
Parasitic leiomyoma in the trocar site after laparoscopic myomectomy: A case report.
Roh C, Kwon H, Jung M World J Clin Cases. 2022; 10(9):2895-2900.
PMID: 35434089 PMC: 8968796. DOI: 10.12998/wjcc.v10.i9.2895.