After the PBDE Phase-out: a Broad Suite of Flame Retardants in Repeat House Dust Samples from California

Overview

Journal Environ Sci Technol

Publisher American Chemical Society

Specialty Environmental Health

Date 2012 Nov 29

PMID 23185960

Citations 130

Authors

Robin E Dodson

Laura J Perovich

Adrian Covaci

Nele Van den Eede

Alin C Ionas

Alin C Dirtu

Julia Green Brody

Ruthann A Rudel

Affiliations

Soon will be listed here.

Abstract

Higher house dust levels of PBDE flame retardants (FRs) have been reported in California than other parts of the world, due to the state's furniture flammability standard. However, changing levels of these and other FRs have not been evaluated following the 2004 U.S. phase-out of PentaBDE and OctaBDE. We analyzed dust collected in 16 California homes in 2006 and again in 2011 for 62 FRs and organohalogens, which represents the broadest investigation of FRs in homes. Fifty-five compounds were detected in at least one sample; 41 in at least 50% of samples. Concentrations of chlorinated OPFRs, including two (TCEP and TDCIPP) listed as carcinogens under California's Proposition 65, were found up to 0.01% in dust, higher than previously reported in the U.S. In 75% of the homes, we detected TDBPP, or brominated "Tris," which was banned in children's sleepwear because of carcinogenicity. To our knowledge, this is the first report on TDBPP in house dust. Concentrations of Firemaster 550 components (EH-TBB, BEH-TEBP, and TPHP) were higher in 2011 than 2006, consistent with its use as a PentaBDE replacement. Results highlight the evolving nature of FR exposures and suggest that manufacturers continue to use hazardous chemicals and replace chemicals of concern with chemicals with uncharacterized toxicity.

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References

Whitehead T, Metayer C, Buffler P, Rappaport S . Estimating exposures to indoor contaminants using residential dust. J Expo Sci Environ Epidemiol. 2011; 21(6):549-64. DOI: 10.1038/jes.2011.11. View

Bearr J, Stapleton H, Mitchelmore C . Accumulation and DNA damage in fathead minnows (Pimephales promelas) exposed to 2 brominated flame-retardant mixtures, Firemaster 550 and Firemaster BZ-54. Environ Toxicol Chem. 2010; 29(3):722-9. PMC: 4332595. DOI: 10.1002/etc.94. View

Kanazawa A, Saito I, Araki A, Takeda M, Ma M, Saijo Y . Association between indoor exposure to semi-volatile organic compounds and building-related symptoms among the occupants of residential dwellings. Indoor Air. 2009; 20(1):72-84. DOI: 10.1111/j.1600-0668.2009.00629.x. View

Petreas M, Nelson D, Brown F, Goldberg D, Hurley S, Reynolds P . High concentrations of polybrominated diphenylethers (PBDEs) in breast adipose tissue of California women. Environ Int. 2010; 37(1):190-7. PMC: 5508731. DOI: 10.1016/j.envint.2010.09.001. View

Van den Eede N, Dirtu A, Neels H, Covaci A . Analytical developments and preliminary assessment of human exposure to organophosphate flame retardants from indoor dust. Environ Int. 2010; 37(2):454-61. DOI: 10.1016/j.envint.2010.11.010. View

Nakari T, Huhtala S . In vivo and in vitro toxicity of decabromodiphenyl ethane, a flame retardant. Environ Toxicol. 2009; 25(4):333-8. DOI: 10.1002/tox.20499. View

Roosens L, Geeraerts C, Belpaire C, Van Pelt I, Neels H, Covaci A . Spatial variations in the levels and isomeric patterns of PBDEs and HBCDs in the European eel in Flanders. Environ Int. 2010; 36(5):415-23. DOI: 10.1016/j.envint.2010.03.001. View

Batterman S, Godwin C, Chernyak S, Jia C, Charles S . Brominated flame retardants in offices in Michigan, USA. Environ Int. 2010; 36(6):548-56. PMC: 4349376. DOI: 10.1016/j.envint.2010.04.008. View

Blum A, Gold M, Ames B, Jones F, Hett E, Dougherty R . Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol. Science. 1978; 201(4360):1020-3. DOI: 10.1126/science.684422. View

10.

Harrad S, Abdallah M, Covaci A . Causes of variability in concentrations and diastereomer patterns of hexabromocyclododecanes in indoor dust. Environ Int. 2008; 35(3):573-9. DOI: 10.1016/j.envint.2008.10.005. View

11.

Stapleton H, Klosterhaus S, Keller A, Ferguson P, van Bergen S, Cooper E . Identification of flame retardants in polyurethane foam collected from baby products. Environ Sci Technol. 2011; 45(12):5323-31. PMC: 3113369. DOI: 10.1021/es2007462. View

12.

Butte W, Heinzow B . Pollutants in house dust as indicators of indoor contamination. Rev Environ Contam Toxicol. 2002; 175:1-46. View

13.

LaA Guardia M, C Hale R, Harvey E . Detailed polybrominated diphenyl ether (PBDE) congener composition of the widely used penta-, octa-, and deca-PBDE technical flame-retardant mixtures. Environ Sci Technol. 2006; 40(20):6247-54. DOI: 10.1021/es060630m. View

14.

Rudel R, Dodson R, Perovich L, Morello-Frosch R, Camann D, Zuniga M . Semivolatile endocrine-disrupting compounds in paired indoor and outdoor air in two northern California communities. Environ Sci Technol. 2010; 44(17):6583-90. PMC: 2930400. DOI: 10.1021/es100159c. View

15.

Rudel R, Camann D, Spengler J, Korn L, Brody J . Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust. Environ Sci Technol. 2003; 37(20):4543-53. DOI: 10.1021/es0264596. View

16.

Zota A, Rudel R, Morello-Frosch R, Brody J . Elevated house dust and serum concentrations of PBDEs in California: unintended consequences of furniture flammability standards?. Environ Sci Technol. 2008; 42(21):8158-64. DOI: 10.1021/es801792z. View

17.

Meeker J, Stapleton H . House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environ Health Perspect. 2010; 118(3):318-23. PMC: 2854757. DOI: 10.1289/ehp.0901332. View

18.

Bergman A, Ryden A, Law R, de Boer J, Covaci A, Alaee M . A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals. Environ Int. 2012; 49:57-82. PMC: 3483428. DOI: 10.1016/j.envint.2012.08.003. View

19.

Garcia M, Rodriguez I, Cela R . Microwave-assisted extraction of organophosphate flame retardants and plasticizers from indoor dust samples. J Chromatogr A. 2006; 1152(1-2):280-6. DOI: 10.1016/j.chroma.2006.11.046. View

20.

Gold M, Blum A, Ames B . Another flame retardant, tris-(1,3-dichloro-2-propyl)-phosphate, and its expected metabolites are mutagens. Science. 1978; 200(4343):785-7. DOI: 10.1126/science.347576. View