Analysis of the Genetic Effects of Prolactin Gene Polymorphisms on Chicken Egg Production

Overview

Journal Mol Biol Rep

Specialty Molecular Biology

Date 2012 Nov 28

PMID 23184001

Citations 4

Authors

Hui-Fang Li

Jing-Ting Shu

Yu-Feng Du

Yan-Ju Shan

Kuan-Wei Chen

Xue-Yu Zhang

Wei Han

Wen-Juan Xu

Affiliations

Soon will be listed here.

Abstract

Chicken prolactin (PRL) is a physiological candidate gene for egg production. Variations of T8052C and G8113C in exon 5 of PRL gene may associate with chicken egg production. The objective of the study was to investigate the association of these two single nucleotide polymorphisms in PRL gene with egg production of Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by polymerase chain reaction-ligase detection reaction (PCR-LDR) method. The T8052C and G8113C of PRL were significantly associated with age at first egg (AFE) and total egg number at 300 days of age (EN 300). A significant association was also found between T8052C-G8113C haplotypes and AFE as well as EN300, the H2H3 was the most advantageous diplotype for egg production. We putatively drew the conclusion that these two SNPs in PRL gene as well as their haplotypes could be used as the potential molecular markers for egg production traits in chicken.

Citing Articles

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