Therapeutic Management of Epithelial Ovarian Cancer During Pregnancy

Overview

Journal Clin Transl Oncol

Specialty Oncology

Date 2012 Nov 27

PMID 23180347

Citations 13

Authors

L Minig

L Otano

I Diaz-Padilla

R Alvarez Gallego

M G Patrono

J Valero de Bernabe

Affiliations

Soon will be listed here.

Abstract

Epithelial ovarian cancer (EOC) during pregnancy is a rare condition. The diagnosis and treatment strategies are therefore not well defined. The evidence is scarce and limited to small case reports or case series. In this review we describe the safety, utility and limitations of each diagnostic tool and surgical procedure in pregnant women with ovarian cancer. We also discuss the role of chemotherapy for ovarian cancer during pregnancy. Finally, we delineate different strategies of treatment according to the stage of the disease at diagnosis and gestational age. Due to the complexity of the management of EOC during pregnancy, patients should be referred to specialized centers. Gestational age at diagnosis, the initial surgical procedure, disease stage and patient's preferences are the key factors in the decision-making process to establish the best treatment strategy for each individual case.

Citing Articles

Multidisciplinary management of pregnancy-associated and early post-partum head and neck cancer patients.

Bergamini C, Cavalieri S, Resteghini C, Alfieri S, Nuzzolese I, Colombo E Front Oncol. 2023; 13:1298439.

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Approaches to the Diagnosis and Management of Ovarian Cancer in Pregnancy.

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Malignant Ovarian Tumors During Pregnancy: A Multicenter Retrospective Analysis.

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Long non-coding RNA SNHG1 is an unfavorable prognostic factor and promotes cell proliferation and migration by Wnt/β-catenin pathway in epithelial ovarian cancer.

Wang S, Jiang J, Wang Z, Xie Y, Wu X Int J Clin Exp Pathol. 2020; 10(9):9284-9292.

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Long-term multidisciplinary integrative therapy management resulted in favorable outcomes for ovarian cancer during pregnancy: a case report and literature review.

Xu T, Wang L, Jia Y, Jia Z, Li Z, Cui S J Ovarian Res. 2019; 12(1):108.

PMID: 31711529 PMC: 6844043. DOI: 10.1186/s13048-019-0584-3.

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