Applications for Preclinical PET/MRI

Overview

Journal Semin Nucl Med

Specialty Nuclear Medicine

Date 2012 Nov 27

PMID 23178086

Citations 32

Authors

Martin S Judenhofer

Simon R Cherry

Affiliations

Soon will be listed here.

Abstract

Currently, the combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its emerging clinical applications but also in the preclinical field. Several prototypes based on several different types of PET detector technology have been developed in recent years, some of which have been used for first preclinical studies. This article provides an overview of currently available PET systems and considerations for combined PET/MRI workflows, and summarizes the results of the first studies performed on dedicated preclinical PET/MRI systems. The article also highlights other research using PET and MRI in combination and highlights potential benefits for integrated systems.

Citing Articles

Fully automated whole brain segmentation from rat MRI scans with a convolutional neural network.

Porter V, Hobson B, Foster B, Lein P, Chaudhari A J Neurosci Methods. 2024; 405:110078.

PMID: 38340902 PMC: 11000587. DOI: 10.1016/j.jneumeth.2024.110078.

Evaluation of the MRI compatibility of PET detectors modules for organ-specific inserts in a 3T and 7T MRI scanner.

Schmidt F, Allen M, Ladebeck R, Breuer J, Judenhofer M, Schmand M Med Phys. 2023; 51(2):991-1006.

PMID: 38150577 PMC: 10923015. DOI: 10.1002/mp.16923.

Development and performance of SIAT bPET: a high-resolution and high-sensitivity MR-compatible brain PET scanner using dual-ended readout detectors.

Kuang Z, Sang Z, Ren N, Wang X, Zeng T, Wu S Eur J Nucl Med Mol Imaging. 2023; 51(2):346-357.

PMID: 37782321 DOI: 10.1007/s00259-023-06458-z.

Advances in PET imaging of cancer.

Schwenck J, Sonanini D, Cotton J, Rammensee H, Fougere C, Zender L Nat Rev Cancer. 2023; 23(7):474-490.

PMID: 37258875 DOI: 10.1038/s41568-023-00576-4.

Performance evaluation of SimPET-L and SimPET-XL: MRI-compatible small-animal PET systems with rat-body imaging capability.

Seo M, Ko G, Kim K, Son J, Byun J, Lee Y EJNMMI Phys. 2023; 10(1):16.

PMID: 36881339 PMC: 9992463. DOI: 10.1186/s40658-023-00534-x.