» Articles » PMID: 23162222

Role of Stem Cells in the Management of Chronic Wounds

Overview
Publisher Thieme
Specialty General Surgery
Date 2012 Nov 20
PMID 23162222
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Chronic wounds continue to be a major challenge for the medical profession, and plastic surgeons are frequently called in to help in the management of such wounds. Apart from the obvious morbidity to the patient, these problem wounds can be a major drain on the already scarce hospital resources. Sometimes, these chronic wounds can be more taxing than the underlying disease itself. Although many newer methods are available to handle such situations, the role of stem cells in the management of such wounds is an exciting area that needs to be explored further. A review of literature has been done regarding the role of stem cells in the management of chronic wounds. The abnormal pathology in such wounds is discussed and the possible role of stem cells for optimal healing in such cases would be detailed.

Citing Articles

The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Mediates the Inflammatory Process in Deep Dermal Burn Injury.

Pakan A, Josh F, Soekamto T, Hendarto J Ann Burns Fire Disasters. 2024; 36(4):320-330.

PMID: 38680233 PMC: 11041994.


Multifunctional and Smart Wound Dressings-A Review on Recent Research Advancements in Skin Regenerative Medicine.

Raju N, Silina E, Stupin V, Manturova N, Chidambaram S, Achar R Pharmaceutics. 2022; 14(8).

PMID: 36015200 PMC: 9414988. DOI: 10.3390/pharmaceutics14081574.


Stem Cell Therapy for Burns: Story so Far.

Abdul Kareem N, Aijaz A, Jeschke M Biologics. 2021; 15:379-397.

PMID: 34511880 PMC: 8418374. DOI: 10.2147/BTT.S259124.


Wound Healing and the Use of Medicinal Plants.

Shedoeva A, Leavesley D, Upton Z, Fan C Evid Based Complement Alternat Med. 2019; 2019:2684108.

PMID: 31662773 PMC: 6778887. DOI: 10.1155/2019/2684108.


Wound healing and fibrosis: current stem cell therapies.

Jones R, Foster D, Hu M, Longaker M Transfusion. 2019; 59(S1):884-892.

PMID: 30737822 PMC: 7089773. DOI: 10.1111/trf.14836.


References
1.
Burd A, Ahmed K, Lam S, Ayyappan T, Huang L . Stem cell strategies in burns care. Burns. 2007; 33(3):282-91. DOI: 10.1016/j.burns.2006.08.031. View

2.
Hedrick M, Daniels E . The use of adult stem cells in regenerative medicine. Clin Plast Surg. 2003; 30(4):499-505. DOI: 10.1016/s0094-1298(03)00068-3. View

3.
Barrandon Y, Green H . Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci U S A. 1987; 84(8):2302-6. PMC: 304638. DOI: 10.1073/pnas.84.8.2302. View

4.
Altman A, Matthias N, Yan Y, Song Y, Bai X, Chiu E . Dermal matrix as a carrier for in vivo delivery of human adipose-derived stem cells. Biomaterials. 2008; 29(10):1431-42. DOI: 10.1016/j.biomaterials.2007.11.026. View

5.
Cha J, Falanga V . Stem cells in cutaneous wound healing. Clin Dermatol. 2007; 25(1):73-8. DOI: 10.1016/j.clindermatol.2006.10.002. View