Post-metabolic Response to Passive Normobaric Hypoxic Exposure in Sedendary Overweight Males: a Pilot Study

Overview

Journal Nutr Metab (Lond)

Publisher Biomed Central

Date 2012 Nov 20

PMID 23157699

Citations 22

Authors

Chad Workman

Fabien A Basset

Affiliations

Soon will be listed here.

Abstract

Unlabelled:

Background: The present pilot study was designed to test the impact of passive acute normobaric hypoxic exposure (PAH) and passive short-term normobaric hypoxic exposure (PSH) conditions on energy expenditure (EE) and substrates utilisation (glucose and lipid oxidation).

Methods: Eleven participants have completed the PAH session while the control group (CG) underwent a simulated experimental condition in normobaric normoxic condition. A subset of 6 participants underwent an additional six 3-hour sessions on consecutive days. Metabolic rates were obtained pre- and post-treatments on the morning following an overnight (12 hours) fast in PAH, PSH, and CG groups.

Results: The statistical outcomes showed a significant increase in EE for PAH, control, and PSH while a shift in substrate utilization towards lipid sources was only detected for PAH and PSH, respectively.

Conclusion: This pilot study showed that passive acute normobaric hypoxic exposure did affect EE and fuel utilization in sedentary overweight males and that further passive normobaric hypoxic exposures (PSH) magnified these metabolic adjustments. These outcomes provide valuable information for further research in the area of hypoxia as a new therapeutic strategy to improve the management of weight loss.

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