Clinical Applications of the Computed Tomography Angiography Spot Sign in Acute Intracerebral Hemorrhage: a Review

Overview

Journal Stroke

Specialties Cardiology & Vascular Diseases
Neurology

Date 2012 Nov 8

PMID 23132779

Citations 39

Authors

H Bart Brouwers

Joshua N Goldstein

Javier M Romero

Jonathan Rosand

Affiliations

Soon will be listed here.

Citing Articles

Dual-energy computed tomography material decomposition improves prediction accuracy of hematoma expansion in traumatic intracranial hemorrhage.

Lee J, Park S, Hwang S, Kim J, Lee A, Chang K PLoS One. 2023; 18(7):e0289110.

PMID: 37498879 PMC: 10374090. DOI: 10.1371/journal.pone.0289110.

Research advances in imaging markers for predicting hematoma expansion in intracerebral hemorrhage: a narrative review.

Huang Y, Huang H, Li Z, Yin X Front Neurol. 2023; 14:1176390.

PMID: 37181553 PMC: 10166819. DOI: 10.3389/fneur.2023.1176390.

MRI spot sign in acute intracerebral hemorrhage: an independent biomarker of hematoma expansion and poor functional outcome.

Valyraki N, Goujon A, Mateos M, Lecoeuvre A, Lecler A, Raynouard I J Neurol. 2022; 270(3):1531-1542.

PMID: 36434128 DOI: 10.1007/s00415-022-11498-w.

Tranexamic Acid for Acute Spontaneous Intracerebral Hemorrhage: A Meta-Analysis of Randomized Controlled Trials.

Guo Y, Guo X, Li R, Zhao K, Bao Q, Yang J Front Neurol. 2022; 12:761185.

PMID: 34987465 PMC: 8720763. DOI: 10.3389/fneur.2021.761185.

European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage.

Sandset E, Anderson C, Bath P, Christensen H, Fischer U, Gasecki D Eur Stroke J. 2021; 6(2):XLVIII-LXXXIX.

PMID: 34780578 PMC: 8370078. DOI: 10.1177/23969873211012133.

References

Fisher C . Pathological observations in hypertensive cerebral hemorrhage. J Neuropathol Exp Neurol. 1971; 30(3):536-50. DOI: 10.1097/00005072-197107000-00015. View

Murai Y, Takagi R, Ikeda Y, Yamamoto Y, Teramoto A . Three-dimensional computerized tomography angiography in patients with hyperacute intracerebral hemorrhage. J Neurosurg. 1999; 91(3):424-31. DOI: 10.3171/jns.1999.91.3.0424. View

Brouwers H, Biffi A, McNamara K, Ayres A, Valant V, Schwab K . Apolipoprotein E genotype is associated with CT angiography spot sign in lobar intracerebral hemorrhage. Stroke. 2012; 43(8):2120-5. PMC: 3426364. DOI: 10.1161/STROKEAHA.112.659094. View

Wang Y, Fan J, Luo G, Lin T, Xie D, Ji F . Hematoma volume affects the accuracy of computed tomographic angiography 'spot sign' in predicting hematoma expansion after acute intracerebral hemorrhage. Eur Neurol. 2011; 65(3):150-5. DOI: 10.1159/000324153. View

Thompson A, Kosior J, Gladstone D, Hopyan J, Symons S, Romero F . Defining the CT angiography 'spot sign' in primary intracerebral hemorrhage. Can J Neurol Sci. 2009; 36(4):456-61. DOI: 10.1017/s0317167100007782. View

Demchuk A, Dowlatshahi D, Rodriguez-Luna D, Molina C, Silva Blas Y, Dzialowski I . Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study. Lancet Neurol. 2012; 11(4):307-14. DOI: 10.1016/S1474-4422(12)70038-8. View

van Asch C, Luitse M, Rinkel G, van der Tweel I, Algra A, Klijn C . Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol. 2010; 9(2):167-76. DOI: 10.1016/S1474-4422(09)70340-0. View

Qureshi A, Palesch Y . Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) II: design, methods, and rationale. Neurocrit Care. 2011; 15(3):559-76. PMC: 3340125. DOI: 10.1007/s12028-011-9538-3. View

Goldstein J, Fazen L, SNIDER R, Schwab K, Greenberg S, Smith E . Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007; 68(12):889-94. DOI: 10.1212/01.wnl.0000257087.22852.21. View

10.

Oleinik A, Romero J, Schwab K, Lev M, Jhawar N, Delgado Almandoz J . CT angiography for intracerebral hemorrhage does not increase risk of acute nephropathy. Stroke. 2009; 40(7):2393-7. PMC: 2726774. DOI: 10.1161/STROKEAHA.108.546127. View

11.

Wada R, Aviv R, Fox A, Sahlas D, Gladstone D, Tomlinson G . CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007; 38(4):1257-62. DOI: 10.1161/01.STR.0000259633.59404.f3. View

12.

Qureshi A, Mendelow A, Hanley D . Intracerebral haemorrhage. Lancet. 2009; 373(9675):1632-44. PMC: 3138486. DOI: 10.1016/S0140-6736(09)60371-8. View

13.

Delgado Almandoz J, Yoo A, Stone M, Schaefer P, Goldstein J, Rosand J . Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke. 2009; 40(9):2994-3000. PMC: 3498504. DOI: 10.1161/STROKEAHA.109.554667. View

14.

Davis S, Broderick J, Hennerici M, Brun N, Diringer M, Mayer S . Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology. 2006; 66(8):1175-81. DOI: 10.1212/01.wnl.0000208408.98482.99. View

15.

dEsterre C, Chia T, Jairath A, Lee T, Symons S, Aviv R . Early rate of contrast extravasation in patients with intracerebral hemorrhage. AJNR Am J Neuroradiol. 2011; 32(10):1879-84. PMC: 7965988. DOI: 10.3174/ajnr.A2669. View

16.

Broderick J, Brott T, Duldner J, Tomsick T, Huster G . Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality. Stroke. 1993; 24(7):987-93. DOI: 10.1161/01.str.24.7.987. View

17.

Flibotte J, Hagan N, ODonnell J, Greenberg S, Rosand J . Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology. 2004; 63(6):1059-64. DOI: 10.1212/01.wnl.0000138428.40673.83. View

18.

Mayer S, Brun N, Begtrup K, Broderick J, Davis S, Diringer M . Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008; 358(20):2127-37. DOI: 10.1056/NEJMoa0707534. View

19.

Delgado Almandoz J, Kelly H, Schaefer P, Brouwers H, Yoo A, Stone M . CT angiography spot sign predicts in-hospital mortality in patients with secondary intracerebral hemorrhage. J Neurointerv Surg. 2011; 4(6):442-7. PMC: 3684202. DOI: 10.1136/neurintsurg-2011-010061. View

20.

Broderick J, Diringer M, Hill M, Brun N, Mayer S, Steiner T . Determinants of intracerebral hemorrhage growth: an exploratory analysis. Stroke. 2007; 38(3):1072-5. DOI: 10.1161/01.STR.0000258078.35316.30. View