Serum Lipids, Lipoproteins and Sex-hormone Binding Globulin in Breast Cancer

Overview

Journal Indian J Clin Biochem

Specialty Biochemistry

Date 2012 Oct 30

PMID 23105300

Citations 1

Authors

A Ray

S L Dayalu Naik

A K Bahadur

S T Pasha

R S Rautela

B K Sharma

Affiliations

Soon will be listed here.

Abstract

Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein (HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically proven cases of breast cancer along with 146 control women. The mean levels of serum triglycerides, total cholesterol and LDL-cholesterol were found to be significantly higher in breast cancer cases as compared to controls. However, lower mean levels of serum HDL-cholesterol and sex-hormone binding glubulin (SHBG) were observed in breast cancer patients than the control subjects. The results indicate a probable relation between serum lipids and the activity of sex-hormones. Moreover, the study reflects an overall disturbance of lipid metabolism in the pathological process of breast cancer.

Citing Articles

A comparitive study to evaluate the role of serum lipid levels in aetiology of carcinoma breast.

Kumar V, Singh A, Sidhu D, Panag K J Clin Diagn Res. 2015; 9(2):PC01-3.

PMID: 25859487 PMC: 4378769. DOI: 10.7860/JCDR/2015/12273.5563.

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