Transamidation of Primary Amides with Amines Catalyzed by Zirconocene Dichloride

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2012 Oct 26

PMID 23097018

Citations 8

Authors

Benjamin N Atkinson

A Rosie Chhatwal

Helen V Lomax

James W Walton

Jonathan M J Williams

Affiliations

Soon will be listed here.

Abstract

Zirconocene dichloride (Cp(2)ZrCl(2)) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80 °C in 5-24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30 °C.

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