Cell-based Interventions for Therapeutic Angiogenesis: Review of Potential Cell Sources
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Alternative therapies are currently being developed to treat patients with chronic limb ischemia who are unable to be revascularized in order to avoid amputation. Cell-based therapy using mononuclear cells is gaining attention as many clinical trials are currently underway. We review cell differentiation along with the different potential cell sources for use in therapeutic angiogenesis.
Bui H, Huy Do D, Ly H, Tran K, Le H, Nguyen K PLoS One. 2024; 19(3):e0290936.
PMID: 38451970 PMC: 10919600. DOI: 10.1371/journal.pone.0290936.
CD34-Structure, Functions and Relationship with Cancer Stem Cells.
Radu P, Zurzu M, Paic V, Bratucu M, Garofil D, Tigora A Medicina (Kaunas). 2023; 59(5).
PMID: 37241170 PMC: 10220851. DOI: 10.3390/medicina59050938.
Supramolecular hydrogels encapsulating bioengineered mesenchymal stem cells for ischemic therapy.
Hwang B, Kim Y, Kim M, Han S, Bok S, Park K RSC Adv. 2022; 8(34):18771-18775.
PMID: 35539688 PMC: 9080606. DOI: 10.1039/c8ra00464a.
CD34 circulating cells display signs of immune activation in patients with acute coronary syndrome.
Riesinger L, Saemisch M, Nickmann M, Methe H Heart Vessels. 2018; 33(12):1559-1569.
PMID: 30003322 DOI: 10.1007/s00380-018-1220-7.
A Murine Model of Hind Limb Ischemia to Study Angiogenesis and Arteriogenesis.
Yu J, Dardik A Methods Mol Biol. 2018; 1717:135-143.
PMID: 29468589 PMC: 5993192. DOI: 10.1007/978-1-4939-7526-6_11.