Impact of Body Mass Index and Gender on Quality of Life in Patients with Gastroesophageal Reflux Disease

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2012 Oct 11

PMID 23049219

Citations 12

Authors

Shou-Wu Lee

Han-Chung Lien

Chi-Sen Chang

Yen-Chun Peng

Chung-Wang Ko

Ming-Chih Chou

Affiliations

Soon will be listed here.

Abstract

Aim: To investigate the symptom presentation and quality of life in obese Chinese patients with gastroesophageal reflux disease (GERD).

Methods: Data from patients diagnosed with GERD according to the Montreal definition, were collected between January 2009 to March 2010. The enrolled patients were assigned to the normal [body mass index (BMI) < 25 kg/m(2)], overweight (25-30 kg/m(2)), and obese (BMI > 30 kg/m(2)) groups. General demographic data, endoscopic findings, and quality of life of the three groups of patients were analyzed and compared.

Results: Among the 173 enrolled patients, 102, 56 and 15 patients were classified in the normal, overweight, and obese, respectively. There was significantly more erosive esophagitis (73.3% vs 64.3% vs 39.2%, P = 0.002), hiatal hernia (60% vs 33.9% vs 16.7%, P = 0.001), and males (73.3% vs 73.2% vs 32.4%, P = 0.001) in the obese cases. The severity and frequency of heartburn, not acid regurgitation, was positively correlated with BMI, with a significant association in men, but not in women. Obese patients were prone to have low quality of life scores, with obese women having the lowest scores for mental health.

Conclusion: In patients with GERD, obese men had the most severe endoscopic and clinical presentation. Obese women had the poorest mental health.

Citing Articles

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Gastroesophageal Reflux Disease in Idiopathic Pulmonary Fibrosis: Viewer or Actor? To Treat or Not to Treat?.

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Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease.

Lee S, Lee T, Lien H, Peng Y, Yeh H, Chang C Gastroenterology Res. 2017; 10(2):78-83.

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Impact of Obesity on a Chinese Population with Erosive Esophagitis and Barrett's Esophagus.

Lee S, Lien H, Lee T, Tung C, Yeh H, Chang C Gut Liver. 2016; 11(3):377-382.

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