Current Status and Future Directions in Gastric Cancer with Peritoneal Dissemination

Overview

Journal Surg Oncol Clin N Am

Specialties General Surgery
Oncology

Date 2012 Oct 2

PMID 23021720

Citations 29

Authors

Gabriel Glockzin

Pompiliu Piso

Affiliations

Soon will be listed here.

Abstract

Peritoneal carcinomatosis arising from gastric cancer is mostly associated with poor prognosis. Despite the improvement of survival with modern polychemotherapy, the results are still unsatisfactory. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy might provide an additional therapeutic option for highly selected patients with gastric cancer and peritoneal metastasis leading to improved prognosis. Considering the increased rate of perioperative morbidity and the crucial prognostic role of complete macroscopic cytoreduction, adequate preoperative diagnostics and patient selection are strongly recommended. Further prospective randomized trials are needed to determine the roles of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy as part of an interdisciplinary treatment concept.

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