Associations of Intake of Antioxidant Vitamins and Fatty Acids with Asthma in Pre-school Children

Overview

Journal Public Health Nutr

Publisher Cambridge University Press

Date 2012 Oct 2

PMID 23021626

Citations 9

Authors

Kozue Nakamura

Keiko Wada

Yukari Sahashi

Yuya Tamai

Michiko Tsuji

Kaori Watanabe

Sakiko Ohtsuchi

Kyoko Ando

Chisato Nagata

Affiliations

Soon will be listed here.

Abstract

Objective: Increasing childhood asthma rates may be due to changing dietary lifestyle. We investigated the association of dietary intake of antioxidant vitamins and fatty acids with asthma in Japanese pre-school children.

Design: Cross-sectional study.

Setting: School-based survey on lifestyle/diet and health status in children in Japan.

Subjects: Parents of 452 children aged 3-6 years completed a questionnaire on the children's and parents’ lifestyle and demographics. Children were classified into asthma cases and non-asthma cases in accordance with the ATS-DLD(American Thoracic Society and Division of Lung Diseases of the National Heart, Lung, and Blood Institute) questionnaire. Children's diet was assessed using a 3 d dietary record completed by parents. Children's age, sex, BMI, history of food allergy, maternal age, parental history of allergy, maternal education,family size and second-hand smoking were included as covariates. Logistic regression models were used to examine the association between children's diet and asthma.

Results: Compared with children with the lowest intake tertile for vitamin C and vitamin E, those in the highest were significantly inversely associated with asthma; adjusted OR (95% CI) were 0?35 (0?14, 0?88) and 0?32 (0?12, 0?85),respectively. A statistically significant trend was also observed. Fruit intake showed an inverse but insignificant association with asthma. There were no associations of any type of fatty acids with asthma.

Conclusions: These data suggest that children with high intakes of vitamins C and E may be associated with a reduced prevalence of asthma.

Citing Articles

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