Orthobunyavirus Antibodies in Humans, Yucatan Peninsula, Mexico

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2012 Sep 29

PMID 23017592

Citations 11

Authors

Bradley J Blitvich

Rungrat Saiyasombat

Lourdes G Talavera-Aguilar

Julian E Garcia-Rejon

Jose A Farfan-Ale

Carlos Machain-Williams

Maria A Lorono-Pino

Affiliations

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Abstract

We performed a serologic investigation to determine whether orthobunyaviruses commonly infect humans in the Yucatan Peninsula of Mexico. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization test in 146 (18%) of 823 persons tested. Further studies are needed to determine health risks for humans from this potentially deadly group of viruses.

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References

Rodriguez M, Rodriguez D, Blitvich B, Lopez M, Fernandez-Salas I, Ramos Jimenez J . Serologic surveillance for West Nile virus and other flaviviruses in febrile patients, encephalitic patients, and asymptomatic blood donors in northern Mexico. Vector Borne Zoonotic Dis. 2009; 10(2):151-7. PMC: 2883485. DOI: 10.1089/vbz.2008.0203. View

Blitvich B, Saiyasombat R, da Rosa A, Tesh R, Calisher C, Garcia-Rejon J . Orthobunyaviruses, a common cause of infection of livestock in the Yucatan peninsula of Mexico. Am J Trop Med Hyg. 2012; 87(6):1132-9. PMC: 3516088. DOI: 10.4269/ajtmh.2012.12-0188. View

Farfan-Ale J, Lorono-Pino M, Garcia-Rejon J, Hovav E, Powers A, Lin M . Detection of RNA from a novel West Nile-like virus and high prevalence of an insect-specific flavivirus in mosquitoes in the Yucatan Peninsula of Mexico. Am J Trop Med Hyg. 2009; 80(1):85-95. PMC: 2663380. View

Calisher C, Lazuick J, Lieb S, Monath T, Castro K . Human infections with Tensaw virus in south Florida: evidence that Tensaw virus subtypes stimulate the production of antibodies reactive with closely related Bunyamwera serogroup viruses. Am J Trop Med Hyg. 1988; 39(1):117-22. DOI: 10.4269/ajtmh.1988.39.117. View

Buescher E, BYRNE R, Clarke G, Gould D, RUSSELL P, Scheider F . Cache Valley virus in the Del Mar Va Peninsula. I. Virologic and serologic evidence of infection. Am J Trop Med Hyg. 1970; 19(3):493-502. DOI: 10.4269/ajtmh.1970.19.493. View