Use of a Prequalification Panel for Rapid Scale-up of High-throughput HIV Viral Load Testing

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2012 Sep 21

PMID 22993182

Citations 6

Authors

Lesley E Scott

Sergio Carmona

Natasha Gous

Pamela Horsfield

Melanie Mackay

Wendy Stevens

Affiliations

Soon will be listed here.

Abstract

Increased access to antiretroviral drugs expands needs for viral load (VL) testing. South Africa's National Health Laboratory Service responded to demands by implementing two testing platforms in 17 laboratories within 8 months. An industry partner's collaboration, training programs, and method verification with a VL prequalification panel ensured testing quality and rapid implementation.

Citing Articles

The Development of a Standardized Quality Assessment Material to Support Xpert HIV-1 Viral Load Testing for ART Monitoring in South Africa.

Noble L, Scott L, Bongwe A, da Silva P, Stevens W Diagnostics (Basel). 2021; 11(2).

PMID: 33499162 PMC: 7911816. DOI: 10.3390/diagnostics11020160.

The Performance of the Abbott Real Time MTB RIF/INH Compared to the MTBDR V2 for the Identification of MDR-TB Among Isolates.

David A, Singh L, da Silva P, Scott L, Stevens W Infect Drug Resist. 2020; 13:3301-3308.

PMID: 33061477 PMC: 7532077. DOI: 10.2147/IDR.S247524.

Performance of the Abbott RealTie MTB and MTB RIF/INH Assays in a Setting of High Tuberculosis and HIV Coinfection in South Africa.

Scott L, David A, Noble L, Nduna M, da Silva P, Black A J Clin Microbiol. 2017; 55(8):2491-2501.

PMID: 28592547 PMC: 5527428. DOI: 10.1128/JCM.00289-17.

Options to Expand HIV Viral Load Testing in South Africa: Evaluation of the GeneXpert® HIV-1 Viral Load Assay.

Gous N, Scott L, Berrie L, Stevens W PLoS One. 2016; 11(12):e0168244.

PMID: 27992495 PMC: 5161463. DOI: 10.1371/journal.pone.0168244.

Laboratory evaluation of the Liat HIV Quant (IQuum) whole-blood and plasma HIV-1 viral load assays for point-of-care testing in South Africa.

Scott L, Gous N, Carmona S, Stevens W J Clin Microbiol. 2015; 53(5):1616-21.

PMID: 25740777 PMC: 4400747. DOI: 10.1128/JCM.03325-14.

References

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Scott L, Carmona S, Stevens W . Performance of the new Roche Cobas AmpliPrep-Cobas TaqMan version 2.0 human immunodeficiency virus type 1 assay. J Clin Microbiol. 2009; 47(10):3400-2. PMC: 2756913. DOI: 10.1128/JCM.00727-09. View

Scott L, Noble L, Moloi J, Erasmus L, Venter W, Stevens W . Evaluation of the Abbott m2000 RealTime human immunodeficiency virus type 1 (HIV-1) assay for HIV load monitoring in South Africa compared to the Roche Cobas AmpliPrep-Cobas Amplicor, Roche Cobas AmpliPrep-Cobas TaqMan HIV-1, and BioMerieux.... J Clin Microbiol. 2009; 47(7):2209-17. PMC: 2708481. DOI: 10.1128/JCM.01761-08. View