Modulating the Modulators: Interaction of Brain Norepinephrine and Cannabinoids in Stress

Overview

Journal Exp Neurol

Specialty Neurology

Date 2012 Sep 18

PMID 22981451

Citations 2

Authors

David A Morilak

Affiliations

Soon will be listed here.

Citing Articles

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility.

Klune C, Jin B, DeNardo L Elife. 2021; 10.

PMID: 33949949 PMC: 8099425. DOI: 10.7554/eLife.64567.

Allostatic load and the cannabinoid system: implications for the treatment of physiological abnormalities in post-traumatic stress disorder (PTSD).

Lohr J, Chang H, Sexton M, Palmer B CNS Spectr. 2019; 25(6):743-749.

PMID: 31303187 PMC: 6960358. DOI: 10.1017/S1092852919001093.

References

Southwick S, Krystal J, Morgan C, Johnson D, Nagy L, Nicolaou A . Abnormal noradrenergic function in posttraumatic stress disorder. Arch Gen Psychiatry. 1993; 50(4):266-74. DOI: 10.1001/archpsyc.1993.01820160036003. View

Kendler K, Karkowski L, Prescott C . Causal relationship between stressful life events and the onset of major depression. Am J Psychiatry. 1999; 156(6):837-41. DOI: 10.1176/ajp.156.6.837. View

Hill M, Hillard C, Bambico F, Patel S, Gorzalka B, Gobbi G . The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. Trends Pharmacol Sci. 2009; 30(9):484-93. DOI: 10.1016/j.tips.2009.06.006. View

Pardon M, Gould G, Garcia A, Phillips L, Cook M, Miller S . Stress reactivity of the brain noradrenergic system in three rat strains differing in their neuroendocrine and behavioral responses to stress: implications for susceptibility to stress-related neuropsychiatric disorders. Neuroscience. 2002; 115(1):229-42. DOI: 10.1016/s0306-4522(02)00364-0. View

Murphy F, Sahakian B, Rubinsztein J, Michael A, Rogers R, Robbins T . Emotional bias and inhibitory control processes in mania and depression. Psychol Med. 2000; 29(6):1307-21. DOI: 10.1017/s0033291799001233. View

Rogers M, Kasai K, Koji M, Fukuda R, Iwanami A, Nakagome K . Executive and prefrontal dysfunction in unipolar depression: a review of neuropsychological and imaging evidence. Neurosci Res. 2004; 50(1):1-11. DOI: 10.1016/j.neures.2004.05.003. View

Cryan J, Page M, Lucki I . Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment. Psychopharmacology (Berl). 2005; 182(3):335-44. DOI: 10.1007/s00213-005-0093-5. View

Kessler R . The effects of stressful life events on depression. Annu Rev Psychol. 1997; 48:191-214. DOI: 10.1146/annurev.psych.48.1.191. View

Turu G, Hunyady L . Signal transduction of the CB1 cannabinoid receptor. J Mol Endocrinol. 2009; 44(2):75-85. DOI: 10.1677/JME-08-0190. View

10.

Austin M, Mitchell P, Goodwin G . Cognitive deficits in depression: possible implications for functional neuropathology. Br J Psychiatry. 2001; 178:200-6. DOI: 10.1192/bjp.178.3.200. View

11.

Hill M, Patel S, Campolongo P, Tasker J, Wotjak C, Bains J . Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output. J Neurosci. 2010; 30(45):14980-6. PMC: 3073528. DOI: 10.1523/JNEUROSCI.4283-10.2010. View

12.

Furmaga H, Shah A, Frazer A . Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats. Biol Psychiatry. 2011; 70(10):937-45. DOI: 10.1016/j.biopsych.2011.07.020. View

13.

Hill M, Gorzalka B . Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test. Eur Neuropsychopharmacol. 2005; 15(6):593-9. DOI: 10.1016/j.euroneuro.2005.03.003. View

14.

Wilson R, Nicoll R . Endocannabinoid signaling in the brain. Science. 2002; 296(5568):678-82. DOI: 10.1126/science.1063545. View

15.

Disner S, Beevers C, Haigh E, Beck A . Neural mechanisms of the cognitive model of depression. Nat Rev Neurosci. 2011; 12(8):467-77. DOI: 10.1038/nrn3027. View

16.

Campos A, Guimaraes F . Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. Prog Neuropsychopharmacol Biol Psychiatry. 2009; 33(8):1517-21. DOI: 10.1016/j.pnpbp.2009.08.017. View

17.

Gobbi G, Bambico F, Mangieri R, Bortolato M, Campolongo P, Solinas M . Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci U S A. 2005; 102(51):18620-5. PMC: 1317988. DOI: 10.1073/pnas.0509591102. View

18.

Fossati P, Amar G, Raoux N, Ergis A, Allilaire J . Executive functioning and verbal memory in young patients with unipolar depression and schizophrenia. Psychiatry Res. 2000; 89(3):171-87. DOI: 10.1016/s0165-1781(99)00110-9. View

19.

Parolaro D, Realini N, Vigano D, Guidali C, Rubino T . The endocannabinoid system and psychiatric disorders. Exp Neurol. 2010; 224(1):3-14. DOI: 10.1016/j.expneurol.2010.03.018. View

20.

Morilak D, Barrera G, Echevarria D, Garcia A, Hernandez A, Ma S . Role of brain norepinephrine in the behavioral response to stress. Prog Neuropsychopharmacol Biol Psychiatry. 2005; 29(8):1214-24. DOI: 10.1016/j.pnpbp.2005.08.007. View