New Advances in the Diagnosis of Typhoid and Detection of Typhoid Carriers
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For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Development of such a test would require antigens that are specific for typhoid diagnosis. Attempts at finding the specific antigen have been carried out throughout the years. The finding of such an antigen can lead to carrier detection as well. Candidate antigens have been used in the development of antigen or antibody detection tests with variation in sensitivity and specificity. Further characterization and understanding of the candidate antigens combined with use of innovative technologies will allow for the ideal test for typhoid and typhoid carriers to be within reach.
Nurmawati S, Alam A, Djauhari H, Merati T, Sudarmono P, Setiawaty V PLoS Negl Trop Dis. 2024; 18(7):e0011848.
PMID: 39052692 PMC: 11315288. DOI: 10.1371/journal.pntd.0011848.
Qureshi S, Maria N, Chawla T, Iqbal J, Kazi A, Adnan M PLoS Negl Trop Dis. 2024; 18(6):e0011775.
PMID: 38865361 PMC: 11168639. DOI: 10.1371/journal.pntd.0011775.
Outbreak of ceftriaxone-resistant serotype Typhi-Tiruchirappalli, Tamil Nadu, India, June 2018.
Dzeyie K, Dhanapaul S, Rubeshkumar P, Desing S, Vignesh M, Raveendran I IJID Reg. 2022; 1:60-64.
PMID: 35757827 PMC: 9216270. DOI: 10.1016/j.ijregi.2021.09.006.
Performance of Immunodiagnostic Tests for Typhoid Fever: A Systematic Review and Meta-Analysis.
Ahmad Najib M, Mustaffa K, Ong E, Selvam K, Khalid M, Awang M Pathogens. 2021; 10(9).
PMID: 34578216 PMC: 8467574. DOI: 10.3390/pathogens10091184.
Roles of Salmonella typhi and Salmonella paratyphi in Gallbladder Cancer Development.
Shukla R, Shukla P, Behari A, Khetan D, Chaudhary R, Tsuchiya Y Asian Pac J Cancer Prev. 2021; 22(2):509-516.
PMID: 33639667 PMC: 8190372. DOI: 10.31557/APJCP.2021.22.2.509.