Gastric and Colonic Metastases from Primary Lung Adenocarcinoma: A Case Report and Review of the Literature

Overview

Journal Oncol Lett

Specialty Oncology

Date 2012 Sep 13

PMID 22970049

Citations 12

Authors

Yen-Min Huang

Tsan-Yu Hsieh

Jim-Ray Chen

Hui-Ping Chien

Pei-Hung Chang

Cheng-Hsu Wang

Jen-Seng Huang

Affiliations

Soon will be listed here.

Abstract

Lung cancer is one of the leading causes of cancer-related mortality worldwide. Gastrointestinal metastasis from primary lung cancer is rare. Only a few reports have been published and the majority of described metastatic sites involved the small intestine. In the present study, we report the first case of primary lung adenocarcinoma with both gastric and colonic metastases. We also review the published literature of primary lung cancer with gastrointestinal metastasis.

Citing Articles

Exploring the multifaceted challenges of gastrointestinal metastases in lung adenocarcinoma: a case report highlighting diagnostic dilemmas and therapeutic innovations.

Xu X, Zhou Q, Chen P, Du C, Huang Y, Gao X Front Oncol. 2024; 14:1486371.

PMID: 39659798 PMC: 11628370. DOI: 10.3389/fonc.2024.1486371.

Surgical indication and management of obstructive colonic metastasis from primary lung adenocarcinoma: report of a case and review of the literature.

Watanabe M, Tsujinaka S, Miura T, Sato Y, Kitamura Y, Sawada K Surg Case Rep. 2024; 10(1):219.

PMID: 39292398 PMC: 11410748. DOI: 10.1186/s40792-024-02016-3.

Intraluminal Small Bowel Metastasis From Primary Lung Cancer.

Kosciuszek N, Noel P, Takabe K, Seitelman E, Datta R, Gunasekaran G World J Oncol. 2023; 13(6):409-416.

PMID: 36660214 PMC: 9822679. DOI: 10.14740/wjon1532.

Symptomatic Colonic Metastasis in a Patient with Non-Small Cell Lung Carcinoma.

Bharwad A, Wuthnow C, Salyers Jr W Kans J Med. 2022; 15:382.

PMID: 36320337 PMC: 9612907. DOI: 10.17161/kjm.vol15.18148.

Gastric Metastasis of Primary Lung Cancer: Case Report and Systematic Review With Pooled Analysis.

Tang D, Lv J, Liu Z, Zhan S, Gao Y Front Oncol. 2022; 12:922016.

PMID: 35875072 PMC: 9304872. DOI: 10.3389/fonc.2022.922016.

References

Grivaux M, Locher C, Jeandel R, Blanchon F . [Intestinal metastases from lung cancer]. Rev Mal Respir. 2006; 23(3 Pt 1):273-6. DOI: 10.1016/s0761-8425(06)71578-9. View

Rossi G, Marchioni A, Romagnani E, Bertolini F, Longo L, Cavazza A . Primary lung cancer presenting with gastrointestinal tract involvement: clinicopathologic and immunohistochemical features in a series of 18 consecutive cases. J Thorac Oncol. 2007; 2(2):115-20. View

Miyazaki K, Satoh H, Sekizawa K . Metastasis to appendix from lung adenocarcinoma. Int J Gastrointest Cancer. 2005; 36(1):59-60. DOI: 10.1385/IJGC:36:1:059. View

McNEILL P, Wagman L, Neifeld J . Small bowel metastases from primary carcinoma of the lung. Cancer. 1987; 59(8):1486-9. DOI: 10.1002/1097-0142(19870415)59:8<1486::aid-cncr2820590815>3.0.co;2-w. View

Lau S, Luthringer D, Eisen R . Thyroid transcription factor-1: a review. Appl Immunohistochem Mol Morphol. 2002; 10(2):97-102. DOI: 10.1097/00129039-200206000-00001. View

Gamez C, Rosell R, Fernandez A, Andia E, Arnaiz M, Cardenal F . PET/CT fusion scan in lung cancer: current recommendations and innovations. J Thorac Oncol. 2007; 1(1):74-7. View

Sugiyama M, Sato A, Oguri S, Sumi K, Tsuboi T, Kurasawa T . [A case of squamous cell lung carcinoma with gastric metastasis diagnosed by gastroendoscopic biopsy]. Nihon Kokyuki Gakkai Zasshi. 2010; 48(9):668-71. View

Renault P, Arotcarena R, Cales V, Lippa A, Benichou M, Laurent P . [Metastatic obstruction of the small bowel revealing or complicating squamous-cell lung cancer. Two cases and a review of the literature]. Rev Pneumol Clin. 2003; 59(3):161-5. View

Chen Z, Wang H . Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine. Am J Surg Pathol. 2004; 28(10):1352-9. DOI: 10.1097/01.pas.0000135520.72965.50. View

10.

Bastos I, Gomes D, Gouveia H, de Freitas D . Colonic metastasis of a lung carcinoma with ileocolic fistula. J Clin Gastroenterol. 1998; 26(4):348. DOI: 10.1097/00004836-199806000-00031. View

11.

Ishii T, Kida K, Katsura H, Yamada K, Jinno S, Kino K . [Large cell carcinoma of the lung with metastasis of the gastric submucosa]. Nihon Ronen Igakkai Zasshi. 1999; 36(6):416-9. DOI: 10.3143/geriatrics.36.416. View

12.

Papaziogas B, Koutelidakis I, Christopoulos P, Doulias T, Paraskevas G, Atmatzidis S . Intestinal Metastasis of a Primary Lung Carcinoma Presenting as Mechanical Small Bowel Obstruction. J Gastrointest Cancer. 2011; 43 Suppl 1:S13-5. DOI: 10.1007/s12029-011-9297-6. View

13.

Hustinx R . PET imaging in assessing gastrointestinal tumors. Radiol Clin North Am. 2004; 42(6):1123-39, ix. DOI: 10.1016/j.rcl.2004.08.003. View

14.

Kawahara K, Akamine S, Takahashi T, Nakamura A, Kusano H, Nakagoe T . Anal metastasis from carcinoma of the lung: report of a case. Surg Today. 1994; 24(12):1101-3. DOI: 10.1007/BF01367465. View

15.

Yamamoto M, Matsuzaki K, Kusumoto H, Uchida H, Mine H, Kabashima A . Gastric metastasis from lung carcinoma. Case report. Hepatogastroenterology. 2002; 49(44):363-5. View

16.

Antler A, Ough Y, Pitchumoni C, Davidian M, Thelmo W . Gastrointestinal metastases from malignant tumors of the lung. Cancer. 1982; 49(1):170-2. DOI: 10.1002/1097-0142(19820101)49:1<170::aid-cncr2820490134>3.0.co;2-a. View

17.

Fletcher M . Gastric perforation secondary to metastatic carcinoma of the lung: a case report. Cancer. 1980; 46(8):1879-82. DOI: 10.1002/1097-0142(19801015)46:8<1879::aid-cncr2820460829>3.0.co;2-a. View

18.

Peng Y, Gu J . Synchronous colorectal and lung cancer: report of three cases. World J Gastroenterol. 2008; 14(6):969-73. PMC: 2687071. DOI: 10.3748/wjg.14.969. View

19.

Barrio J, Arriola J, San Vicente M, Cosme A, Castiella A, Gil Lasa I . [Bleeding of the upper digestive tract due to gastric metastasis of squamous lung carcinoma]. Gastroenterol Hepatol. 1999; 22(8):405-7. View

20.

Shiono S, Masaoka T, Sato T, Yanagawa N . [Positron emission tomography (PET)-computed tomography (CT) suggesting small intestinal metastasis from lung cancer; report of a case]. Kyobu Geka. 2006; 59(5):426-9. View