Hypoglycemia, Hormones and Cytokines in Fatal Meningococcal Septicemia

Overview

Journal J Endocrinol Invest

Publisher Springer

Specialty Endocrinology

Date 1990 Oct 1

PMID 2292658

Citations 8

Authors

J A Romijn

M H Godfried

C Wortel

H P Sauerwein

Affiliations

Soon will be listed here.

Abstract

A unique case report with sequential measurements of the plasma concentrations of glucoregulatory hormones, interleukin-6 and tumor necrosis factor during development of hypoglycemia in fatal meningococcemia is presented. Hormonal explanations for hypoglycemia like hyperinsulinemia or defective hypoglycemic counter-regulation were excluded. Plasma concentrations of interleukin-6 and tumor necrosis factor were skyhigh. The putative relation between cytokines and hypoglycemia in sepsis is discussed.

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