Difficult-to-treat Infections

Overview

Journal Intensive Care Med

Specialty Critical Care

Date 1990 Jan 1

PMID 2289998

Citations 1

Authors

S de Marie

Affiliations

Soon will be listed here.

Abstract

The most common problems in the management of serious bacterial infections were reviewed. As illustrations, the diagnostic and therapeutic strategies in two types of deep-seated infections--both associated with a poor penetration of antibiotics--were discussed: (1) In suppurative central venous thrombophlebitis, conservative therapy frequently fails; if so, one should promptly switch to a surgical approach; (2) in most patients with a parapharyngeal space infection, a non-surgical approach can be recommended including early diagnosis by computed tomography (CT), CT-guided needle aspiration, prompt administration of benzylpenicillin in high and frequent dosages or continuously, and follow-up by CT. This regimen may prevent radical surgery even in the presence of deep neck or mediastinal abscesses.

Citing Articles

Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe.

Hernandez F, Huang L, Olson M, Powers K, Hernandez L, Meyerholz D Nat Med. 2014; 20(3):301-6.

PMID: 24487433 PMC: 3949172. DOI: 10.1038/nm.3460.

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