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Aging and Bone Health in Individuals with Developmental Disabilities

Overview
Publisher Wiley
Specialty Endocrinology
Date 2012 Aug 14
PMID 22888344
Citations 11
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Abstract

Low bone mass density (BMD), a classical age-related health issue and a known health concern for fair skinned, thin, postmenopausal Caucasian women, is found to be common among individuals with developmental/intellectual disabilities (D/IDs). It is the consensus that BMD is decreased in both men and women with D/ID. Maintaining good bone health is important for this population as fractures could potentially go undetected in nonverbal individuals, leading to increased morbidity and a further loss of independence. This paper provides a comprehensive overview of bone health of adults with D/ID, their risk of fractures, and how this compares to the general aging population. We will specifically focus on the bone health of two common developmental disabilities, Down syndrome (DS) and cerebral palsy (CP), and will discuss BMD and fracture rates in these complex populations. Gaining a greater understanding of how bone health is affected in individuals with D/ID could lead to better customized treatments for these specific populations.

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References
1.
Geusens P . Review of guidelines for testing and treatment of osteoporosis. Curr Osteoporos Rep. 2005; 1(2):59-65. DOI: 10.1007/s11914-003-0010-y. View

2.
Kao C, Chen C, Wang S, Yeh S . Bone mineral density in children with Down's syndrome detected by dual photon absorptiometry. Nucl Med Commun. 1992; 13(10):773-5. View

3.
Graafmans W, Ooms M, Hofstee H, Bezemer P, Bouter L, Lips P . Falls in the elderly: a prospective study of risk factors and risk profiles. Am J Epidemiol. 1996; 143(11):1129-36. DOI: 10.1093/oxfordjournals.aje.a008690. View

4.
Tyler Jr C, Snyder C, Zyzanski S . Screening for osteoporosis in community-dwelling adults with mental retardation. Ment Retard. 2000; 38(4):316-21. DOI: 10.1352/0047-6765(2000)038<0316:SFOICA>2.0.CO;2. View

5.
Chen C, Ke J, Wang C, Wu K, Wu C, Wong A . Factors associated with bone density in different skeletal regions in children with cerebral palsy of various motor severities. Dev Med Child Neurol. 2010; 53(2):131-6. DOI: 10.1111/j.1469-8749.2010.03809.x. View