» Articles » PMID: 22833826

Immunotherapy - Vaccines for Allergic Diseases

Overview
Journal J Thorac Dis
Specialty Pulmonary Medicine
Date 2012 Jul 27
PMID 22833826
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Allergic diseases are some of the most commonly encountered problems in clinical practice. Drugs such as corticosteroids and antihistamines can provide effective symptomatic relief, but do not alter the course of the disease. Specific immunotherapy (SIT) was first used to treat pollen allergy in 1911, and has since evolved into an effective treatment for allergic rhinitis and asthma. SIT has been shown in clinical studies to reduce symptoms and medication use in patients with allergic rhinitis and asthma. Recent studies also showed that the therapeutic benefit is long-lasting after the completion of three to five years of treatment. SIT can also effectively reduce the risk of developing asthma and new allergic sensitizations in children with allergic rhinitis.

Citing Articles

Interpreting epidemiologic distribution of total and specific IgE levels for food allergy in Southern China from 2004 to 2023: understanding the mechanisms and focusing on prevention.

Liu M, Liu L, Qi W, Zheng X, Chen J, Yao J BMC Public Health. 2024; 24(1):3022.

PMID: 39482634 PMC: 11529331. DOI: 10.1186/s12889-024-20470-4.


Study of Allergen Patterns in Cases of Moderate to Severe Persistent Allergic Rhinitis in Central India.

Jain S, Jain A, Gupta S Indian J Otolaryngol Head Neck Surg. 2022; 74(Suppl 2):888-893.

PMID: 36452541 PMC: 9702131. DOI: 10.1007/s12070-020-01954-2.


Human immunology and immunotherapy: main achievements and challenges.

Varade J, Magadan S, Gonzalez-Fernandez A Cell Mol Immunol. 2020; 18(4):805-828.

PMID: 32879472 PMC: 7463107. DOI: 10.1038/s41423-020-00530-6.


Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research.

Johnson L, Duschl A, Himly M Vaccines (Basel). 2020; 8(2).

PMID: 32443671 PMC: 7349961. DOI: 10.3390/vaccines8020237.


DNA Nanostructure as an Efficient Drug Delivery Platform for Immunotherapy.

Chi Q, Yang Z, Xu K, Wang C, Liang H Front Pharmacol. 2020; 10:1585.

PMID: 32063844 PMC: 6997790. DOI: 10.3389/fphar.2019.01585.


References
1.
Naclerio R, Proud D, Moylan B, Balcer S, Freidhoff L, Lichtenstein L . A double-blind study of the discontinuation of ragweed immunotherapy. J Allergy Clin Immunol. 1997; 100(3):293-300. DOI: 10.1016/s0091-6749(97)70240-9. View

2.
Walker S, Varney V, Gaga M, Jacobson M, Durham S . Grass pollen immunotherapy: efficacy and safety during a 4-year follow-up study. Allergy. 1995; 50(5):405-13. DOI: 10.1111/j.1398-9995.1995.tb01170.x. View

3.
Kuehr J, Brauburger J, Zielen S, Schauer U, Kamin W, von Berg A . Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis. J Allergy Clin Immunol. 2002; 109(2):274-80. DOI: 10.1067/mai.2002.121949. View

4.
Durham S, Walker S, Varga E, Jacobson M, OBrien F, Noble W . Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med. 1999; 341(7):468-75. DOI: 10.1056/NEJM199908123410702. View

5.
Zielen S, Kardos P, Madonini E . Steroid-sparing effects with allergen-specific immunotherapy in children with asthma: a randomized controlled trial. J Allergy Clin Immunol. 2010; 126(5):942-9. DOI: 10.1016/j.jaci.2010.06.002. View