Hemodynamic Management of Cardiovascular Failure by Using PCO(2) Venous-arterial Difference

Overview

Journal J Clin Monit Comput

Publisher Springer

Specialties Anesthesiology
General Medicine
Medical Informatics

Date 2012 Jul 26

PMID 22828858

Citations 17

Authors

Martin Dres

Xavier Monnet

Jean-Louis Teboul

Affiliations

Soon will be listed here.

Abstract

The difference between mixed venous blood carbon dioxide tension (PvCO(2)) and arterial carbon dioxide tension (PaCO(2)), called ∆PCO(2) has been proposed to better characterize the hemodynamic status. It depends on the global carbon dioxide (CO(2)) production, on cardiac output and on the complex relation between CO(2) tension and CO(2) content. The aim of this review is to detail the physiological background allowing adequate interpretation of ∆PCO(2) at the bedside. Clinical and experimental data support the use of ∆PCO(2) as a valuable help in the decision-making process in patients with hemodynamic instability. The difference between central venous CO(2) tension and arterial CO(2) tension, which is easy to obtain can substitute for ∆PCO(2) to assess the adequacy of cardiac output. Differences between local tissue CO(2) tension and arterial CO(2) tension can also be obtained and provide data on the adequacy of local blood flow to the local metabolic conditions.

Citing Articles

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