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An Integrated Chip for the High-throughput Synthesis of Transcription Activator-like Effectors

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Specialty Chemistry
Date 2012 Jul 24
PMID 22821513
Citations 24
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Abstract

A TALE of two assays: Transcription activator-like effectors (TALEs) are programmable proteins that can specifically recognize a DNA sequence. Previous strategies for the synthesis of TALEs were complicated and time-consuming. The solid-phase synthesis strategy demonstrated here allows quick and simple purification of the ligation product.

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