Ocular Manifestations of Systemic Lupus Erythematosus: a Review of the Literature

Overview

Journal Autoimmune Dis

Publisher Wiley

Date 2012 Jul 20

PMID 22811887

Citations 79

Authors

Neal V Palejwala

Harpreet S Walia

Steven Yeh

Affiliations

Soon will be listed here.

Abstract

About one-third of patients suffering from systemic lupus erythematosus have ocular manifestations. The most common manifestation is keratoconjunctivitis sicca. The most vision threatening are retinal vasculitis and optic neuritis/neuropathy. Prompt diagnosis and treatment of eye disease is paramount as they are often associated with high levels of systemic inflammation and end-organ damage. Initial management with high-dose oral or IV corticosteroids is often necessary. Multiple "steroid-sparing" treatment options exist with the most recently studied being biologic agents.

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