Migraine and Risk of Incident Diabetes in Women: a Prospective Study

Overview

Journal Cephalalgia

Specialties Neurology
Psychiatry

Date 2012 Jul 19

PMID 22807568

Citations 12

Authors

Rebecca C Burch

Pamela M Rist

Anke C Winter

Julie E Buring

Aruna D Pradhan

Elizabeth W Loder

Tobias Kurth

Affiliations

Soon will be listed here.

Abstract

Background: Previous cross-sectional studies evaluating the relationship between diabetes prevalence and migraine status have found conflicting results. We examined the relationship between migraine and incident type 2 diabetes (T2D) in a cohort of adult women.

Methods: Prospective cohort study conducted among participants in the Women's Health Study who provided information on migraine and did not have diabetes at baseline. Our four exposure groups were migraine with aura, migraine without aura, past history of migraine and no history of migraine. Cox proportional hazards models were used to determine the hazard ratio for incident T2D.

Results: Among the 38,620 women included in this study, 5062 (13.1%) women had migraine, of whom 2014 (39.8%) reported migraine with aura, and 2087 (5.4%) women had a past history of migraine. During a mean of 14.6 years of follow-up, there were 3032 cases of incident T2D. After adjustment for confounders, the hazard ratio (95% confidence interval) for developing diabetes was 1.06 (0.91-1.24) for women with migraine with aura, 1.01 (0.89-1.16) for women with migraine without aura, and 1.13 (0.98-1.30) for women with a past history of migraine compared with women with no history of migraine.

Conclusion: Results of this prospective study in women do not support an association between migraine and incident T2D.

Citing Articles

Epidemiological linkage between migraine and diabetes mellitus: a systematic review and meta-analysis.

Ha W, Nguyen V, Chu M J Headache Pain. 2024; 25(1):158.

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Medical comorbidities and other factors associated with migraine among individuals with diabetes mellitus in Hungary: a cross-sectional study using European Health Interview Surveys 2009-2019.

Varga E, Ghanem A, Faludi E, Nguyen C, Kovacs N, Nagy A Front Endocrinol (Lausanne). 2024; 15:1379127.

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Gender Differences in Insulin Resistance: New Knowledge and Perspectives.

Ciarambino T, Crispino P, Guarisco G, Giordano M Curr Issues Mol Biol. 2023; 45(10):7845-7861.

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Islam M, Nyholt D Genes (Basel). 2022; 13(5).

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Migraine and Medical Ramifications: A Comprehensive Overview Based on Observational Study Meta-Analyses.

Chen W, Qian W, Zhong L, Jing G Front Neurol. 2022; 12:778062.

PMID: 35002929 PMC: 8739214. DOI: 10.3389/fneur.2021.778062.

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