Dental Crowding: the Role of Genetics and Tooth Wear

Overview

Journal Angle Orthod

Specialty Dentistry

Date 2012 Jul 18

PMID 22799527

Citations 14

Authors

David Normando

Marco A O Almeida

Catia C A Quintao

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the role of genetics and tooth wear in the etiology of dental crowding through the analysis of a split indigenous Amazon population.

Materials And Methods: Dental crowding prevalence (n = 117), tooth wear (n = 117), and inbreeding coefficient (n = 288) were compared for both villages. A biometric investigation was performed by dental cast analysis of 55 individuals with no tooth loss. Mann-Whitney statistics, independent t-tests, and Fisher exact tests were used at P < .05.

Results: A high coefficient of inbreeding was confirmed in the resultant village (F = 0.25, P < .001). Tooth wear was not significantly different (P = .99), while a significantly higher prevalence of dental crowding was confirmed in the original village (PR = 6.67, P = 0.02). Forty dental arches (n = 20) were examined in the new group, and only one (2.5%) had a dental crowding ≥ 5 mm. In the original villages, we found 20 arches (28.6%) with dental crowding. No difference was observed for tooth size, while larger dental arch dimensions explained a lower level of dental crowding in the resultant village.

Conclusions: Our findings downplay the widespread influence of tooth wear, a direct evidence of what an individual ate in the past, on dental crowding and emphasize the role of heredity, exacerbated through inbreeding, in the etiology of this malocclusion.

Citing Articles

Tooth wear and tertiary crowding: a 13-year cohort study in Amazon Indigenous populations.

Bastos R, da Costa E, Normando D Prog Orthod. 2025; 26(1):1.

PMID: 39757290 PMC: 11700962. DOI: 10.1186/s40510-024-00550-2.

Mandibular Crowding: Diagnosis and Management-A Scoping Review.

Patano A, Malcangi G, Inchingolo A, Garofoli G, De Leonardis N, Azzollini D J Pers Med. 2023; 13(5).

PMID: 37240944 PMC: 10222176. DOI: 10.3390/jpm13050774.

The Effect of Third Molars on the Mandibular Anterior Crowding Relapse-A Systematic Review.

Lyros I, Vasoglou G, Lykogeorgos T, Tsolakis I, Maroulakos M, Fora E Dent J (Basel). 2023; 11(5).

PMID: 37232782 PMC: 10217727. DOI: 10.3390/dj11050131.

Assessing the morphological characteristics of teeth and dental arches as potential predictors of dental crowding.

Daoud R, Bencze M, Albu C, Teodorescu E, Dragomirescu A, Dinca O Med Pharm Rep. 2023; 96(2):211-220.

PMID: 37197272 PMC: 10184532. DOI: 10.15386/mpr-2557.

Association between Eruption Sequence of Posterior Teeth, Dental Crowding, Arch Dimensions, Incisor Inclination, and Skeletal Growth Pattern.

Garcia-Gil M, Alarcon J, Cacho A, Yanez-Vico R, Palma-Fernandez J, Martin C Children (Basel). 2023; 10(4).

PMID: 37189923 PMC: 10137228. DOI: 10.3390/children10040674.

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