» Articles » PMID: 22789644

The Tingathe Programme: a Pilot Intervention Using Community Health Workers to Create a Continuum of Care in the Prevention of Mother to Child Transmission of HIV (PMTCT) Cascade of Services in Malawi

Abstract

Introduction: Loss to follow-up is a major challenge in the prevention of mother to child transmission of HIV (PMTCT) programme in Malawi with reported loss to follow-up of greater than 70%. Tingathe-PMTCT is a pilot intervention that utilizes dedicated community health workers (CHWs) to create a complete continuum of care within the PMTCT cascade, improving service utilization and retention of mothers and infants. We describe the impact of the intervention on longitudinal care starting with diagnosis of the mother at antenatal care (ANC) through final diagnosis of the infant.

Methods: PMTCT service utilization, programme retention and outcomes were evaluated for pregnant women living with HIV and their exposed infants enrolled in the Tingathe-PMTCT programme between March 2009 and March 2011. Multivariate logistic regression was done to evaluate maternal factors associated with failure to complete the cascade.

Results: Over 24 months, 1688 pregnant women living with HIV were enrolled. Median maternal age was 27 years (IQR, 23.8 to 30.8); 333 (19.7%) were already on ART. Among the remaining women, 1328/1355 (98%) received a CD4 test, with 1243/1328 (93.6%) receiving results. Of the 499 eligible for ART, 363 (72.8%) were successfully initiated. Prior to, delivery there were 93 (5.7%) maternal/foetal deaths, 137 (8.1%) women transferred/moved, 51 (3.0%) were lost and 58 (3.4%) refused ongoing PMTCT services. Of the 1318 live births to date, 1264 (95.9%) of the mothers and 1285 (97.5%) of the infants received ARV prophylaxis; 1064 (80.7%) infants were tested for HIV by PCR and started on cotrimoxazole. Median age at PCR was 1.7 months (IQR, 1.5 to 2.5). Overall transmission at first PCR was 43/1047 (4.1%). Of the 43 infants with positive PCR results, 36 (83.7%) were enrolled in ART clinic and 33 (76.7%) were initiated on ART.

Conclusions: Case management and support by dedicated CHWs can create a continuum of longitudinal care in the PMTCT cascade and result in improved outcomes.

Citing Articles

'I no longer worry about money for transport to the health centre' - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: experiences and lessons from the 'Towards an AIDS Free Generation....

Rujumba J, Roebersen C, Namara S, Ochen R, Ahumuza S, Tushabe A BMC Health Serv Res. 2025; 25(1):203.

PMID: 39905401 PMC: 11792326. DOI: 10.1186/s12913-025-12303-w.


Exploring Intervention Frameworks to Improve Utilization of Elimination of Mother-to-Child Transmission Services in Africa: A Scoping Review.

Mukomafhedzi N, Tshitangano T, Tshivhase S Nurs Rep. 2024; 14(3):2580-2595.

PMID: 39330744 PMC: 11434906. DOI: 10.3390/nursrep14030190.


Examining the feasibility of assisted index case testing for HIV case-finding: a qualitative analysis of barriers and facilitators to implementation in Malawi.

Meek C, Munkhondya T, Mphande M, Tembo T, Chitani M, Jean-Baptiste M BMC Health Serv Res. 2024; 24(1):606.

PMID: 38720312 PMC: 11080127. DOI: 10.1186/s12913-024-10988-z.


Phone-based psychosocial counseling for people living with HIV: Feasibility, acceptability and impact on uptake of psychosocial counseling services in Malawi.

Cox C, Masiano S, Mazenga A, Stark M, Udedi M, Simon K Glob Ment Health (Camb). 2024; 11:e3.

PMID: 38283875 PMC: 10808978. DOI: 10.1017/gmh.2023.84.


Does a blended learning implementation package enhance HIV index case testing in Malawi? A protocol for a cluster randomised controlled trial.

Tembo T, Mollan K, Simon K, Rutstein S, Chitani M, Saha P BMJ Open. 2024; 14(1):e077706.

PMID: 38253452 PMC: 10806658. DOI: 10.1136/bmjopen-2023-077706.


References
1.
Mofenson L . Successes and challenges in the perinatal HIV-1 epidemic in the United States as illustrated by the HIV-1 Serosurvey of childbearing women. Arch Pediatr Adolesc Med. 2004; 158(5):422-5. DOI: 10.1001/archpedi.158.5.422. View

2.
Lehmann U, Van Damme W, Barten F, Sanders D . Task shifting: the answer to the human resources crisis in Africa?. Hum Resour Health. 2009; 7:49. PMC: 2705665. DOI: 10.1186/1478-4491-7-49. View

3.
Braun M, Kabue M, McCollum E, Ahmed S, Kim M, Aertker L . Inadequate coordination of maternal and infant HIV services detrimentally affects early infant diagnosis outcomes in Lilongwe, Malawi. J Acquir Immune Defic Syndr. 2011; 56(5):e122-8. PMC: 3112277. DOI: 10.1097/QAI.0b013e31820a7f2f. View

4.
Rollins N, Mzolo S, Moodley T, Esterhuizen T, van Rooyen H . Universal HIV testing of infants at immunization clinics: an acceptable and feasible approach for early infant diagnosis in high HIV prevalence settings. AIDS. 2009; 23(14):1851-7. DOI: 10.1097/QAD.0b013e32832d84fd. View

5.
. Mother-to-child transmission of HIV infection in the era of highly active antiretroviral therapy. Clin Infect Dis. 2005; 40(3):458-65. DOI: 10.1086/427287. View