Ethyl Cyanoacetate: a New Cyanating Agent for the Palladium-catalyzed Cyanation of Aryl Halides

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2012 Jul 13

PMID 22783893

Citations 7

Authors

Shuyan Zheng

Chunhui Yu

Zhengwu Shen

Affiliations

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Abstract

A new Pd-catalyzed cyanation reaction has been discovered using ethyl cyanoacetate as the cyanating reagent. A variety of electron-rich and electron-deficient aryl halides were efficiently converted into their corresponding nitriles in good to excellent yields.

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