Frequency and Predictors of Endoleaks and Long-term Patency After Covered Stent Placement for the Treatment of Intracranial Aneurysms: a Prospective, Non-randomised Multicentre Experience

Overview

Journal Eur Radiol

Specialty Radiology

Date 2012 Jul 12

PMID 22782569

Citations 20

Authors

Yue-Qi Zhu

Ming-Hua Li

Feng Lin

Dong-Lei Song

Hua-Qiao Tan

Bin-Xian Gu

Hong-Qi Zhang

Bin Leng

Pei-Lei Zhang

Affiliations

Soon will be listed here.

Abstract

Objective: We investigated immediate/late endoleaks and long-term patency following stent-graft placement for treatment of intracranial aneurysms located within the distal internal carotid artery (ICA) or vertebral artery (VA).

Methods: Forty-five aneurysms in 41 patients receiving covered stents in three centres were followed. Outcome measures included aneurysm occlusion rate, endoleaks, late in-stent stenosis rate, clinical improvement, neurological deficiencies and death.

Results: Total aneurysm exclusion was achieved in 69.2% (n = 27), with 30.8% (n = 12) experiencing immediate residual endoleaks. Angiographic follow-up (mean 43.5 ± 14.3 months) revealed that 87.2% (n = 34) were completely occluded with only 12.8% (n = 5) showing residual endoleaks. Predictors of immediate endoleaks in our patient group were stent number (P = 0.023) and stent diameter (P = 0.022), while predictors of late endoleaks in our patient group were stent diameter (P = 0.035) and stent angulation (P = 0.021). Late in-stent stenosis rates were 18.0 ± 13.3 and 29.0 ± 18.5% compared with the period immediately following implantation at 2- and 6-year follow-ups respectively. Smoking (P = 0.017) and stent angulation (P = 0.020) were predictors of late in-stent stenosis.

Conclusion: Treating intracranial aneurysms with Willis stent-grafts has an acceptable immediate and late occlusion rate and long-term stented artery patency rate.

Citing Articles

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Ma L, Yan S, Feng H, Xu J, Tan H, Fang C J Interv Med. 2022; 4(4):212-218.

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