Genetic Algorithms and Evolution
Overview
Affiliations
The genetic algorithm (GA) as developed by Holland (1975, Adaptation in Natural and Artificial Systems. Ann Arbor: University of Michigan Press) is an optimization technique based on natural selection. We use a modified version of this technique to investigate which aspects of natural selection make it an efficient search procedure. Our main modification to Holland's GA is the subdividing of the population into semi-isolated demes. We consider two examples. One is a fitness landscape with many local optima. The other is a model of singing in birds that has been previously analysed using dynamic programming. Both examples have epistatic interactions. In the first example we show that the GA can find the global optimum and that its success is improved by subdividing the population. In the second example we show that GAs can evolve to the optimal policy found by dynamic programming.
The development and validation of a prediction model for post-AKI outcomes of pediatric inpatients.
Zhang C, Liu X, Yan R, Nie X, Peng Y, Zhou N Clin Kidney J. 2025; 18(2):sfaf007.
PMID: 39991652 PMC: 11843026. DOI: 10.1093/ckj/sfaf007.
Extending Genetic Algorithms with Biological Life-Cycle Dynamics.
Felix-Saul J, Garcia-Valdez M, Merelo Guervos J, Castillo O Biomimetics (Basel). 2024; 9(8).
PMID: 39194455 PMC: 11351250. DOI: 10.3390/biomimetics9080476.
Lin Y, Li J, Ruan X, Huang X, Zhang J PeerJ Comput Sci. 2023; 9:e1632.
PMID: 38077544 PMC: 10703079. DOI: 10.7717/peerj-cs.1632.
miRDM-rfGA: Genetic algorithm-based identification of a miRNA set for detecting type 2 diabetes.
Park A, Nam S BMC Med Genomics. 2023; 16(1):195.
PMID: 37608331 PMC: 10463588. DOI: 10.1186/s12920-023-01636-2.
Kang B, Park A, Yang H, Jo Y, Oh T, Jeong S Sci Rep. 2022; 12(1):21842.
PMID: 36528695 PMC: 9759583. DOI: 10.1038/s41598-022-26102-4.