» Articles » PMID: 22773801

Acute Lymphoblastic Leukemia

Abstract

The inaugural NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for acute lymphoblastic leukemia (ALL) were developed as a result of meetings convened by a multi-disciplinary panel of experts in 2011. These NCCN Guidelines provide recommendations on the diagnostic evaluation and workup for ALL, risk assessment, risk-stratified treatment approaches based on the Philadelphia chromosome status and age (adults vs. adolescents/young adults), assessment of minimal residual disease, and supportive care considerations. It is recommended that patients be treated at specialized centers with expertise in the management of ALL.

Citing Articles

Molecular significance of circRNAs in malignant lymphoproliferative disorders: pathogenesis and novel biomarkers or therapeutic targets.

Long B, Wang Y, Hao S, Shi G Am J Cancer Res. 2024; 14(9):4633-4651.

PMID: 39417189 PMC: 11477815. DOI: 10.62347/KMWB5164.


GLP and G9a histone methyltransferases as potential therapeutic targets for lymphoid neoplasms.

Silva-Carvalho A, Filiu-Braga L, Bogea G, de Assis A, Pittella-Silva F, Saldanha-Araujo F Cancer Cell Int. 2024; 24(1):243.

PMID: 38997742 PMC: 11249034. DOI: 10.1186/s12935-024-03441-y.


Allogeneic haematopoietic stem cell transplantation might overcome the poor prognosis of adolescents and adult patients with T-lineage acute lymphoblastic leukaemia and CDKN2 deletion.

Hu X, Wang Z, Qin Y, Xu J, Xu N, Wang Q Bone Marrow Transplant. 2024; 59(8):1146-1153.

PMID: 38769349 DOI: 10.1038/s41409-024-02306-2.


Pulmonary function is a strong predictor of 2-year overall survival and non-relapse mortality after allogenic hematopoietic cell transplantation.

Schierbeck F, Mortensen J, Andersen N, Friis L, Kornblit B, Petersen S Eur J Haematol. 2022; 110(1):50-59.

PMID: 36153797 PMC: 10092052. DOI: 10.1111/ejh.13869.


Isolated Myeloperoxidase Immunohistochemical Expression in Bone Marrow Biopsy Depicts Clinical Outcomes in Adults with Typical B-Acute Lymphoblastic Leukemia.

Fawzy M, Abd El-hafez A, El-Ashwah S, Abouzeid T, Waheeb M, Saif M Asian Pac J Cancer Prev. 2021; 22(7):2143-2152.

PMID: 34319037 PMC: 8607084. DOI: 10.31557/APJCP.2021.22.7.2143.