Arabinogalactan-proteins and the Research Challenges for These Enigmatic Plant Cell Surface Proteoglycans

Overview

Journal Front Plant Sci

Date 2012 Jul 4

PMID 22754559

Citations 80

Authors

Li Tan

Allan M Showalter

Jack Egelund

Arianna Hernandez-Sanchez

Monika S Doblin

Antony Bacic

Affiliations

Soon will be listed here.

Abstract

Arabinogalactan-proteins (AGPs) are complex glycoconjugates that are commonly found at the cell surface and in secretions of plants. Their location and diversity of structures have made them attractive targets as modulators of plant development but definitive proof of their direct role(s) in biological processes remains elusive. Here we overview the current state of knowledge on AGPs, identify key challenges impeding progress in the field and propose approaches using modern bioinformatic, (bio)chemical, cell biological, molecular and genetic techniques that could be applied to redress these gaps in our knowledge.

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References

Ellis M, Egelund J, Schultz C, Bacic A . Arabinogalactan-proteins: key regulators at the cell surface?. Plant Physiol. 2010; 153(2):403-19. PMC: 2879789. DOI: 10.1104/pp.110.156000. View

Schibeci A, Pnjak A, Fincher G . Biosynthesis of arabinogalactan-protein in Lolium multiflorum (Italian ryegrass) endosperm cells. Subcellular distribution of galactosyltransferases. Biochem J. 1984; 218(2):633-6. PMC: 1153383. DOI: 10.1042/bj2180633. View

Oka T, Saito F, Shimma Y, Yoko-O T, Nomura Y, Matsuoka K . Characterization of endoplasmic reticulum-localized UDP-D-galactose: hydroxyproline O-galactosyltransferase using synthetic peptide substrates in Arabidopsis. Plant Physiol. 2009; 152(1):332-40. PMC: 2799367. DOI: 10.1104/pp.109.146266. View

Yang J, Zhang Y, Liang Y, Showalter A . Expression analyses of AtAGP17 and AtAGP19, two lysine-rich arabinogalactan proteins, in Arabidopsis. Plant Biol (Stuttg). 2011; 13(3):431-8. DOI: 10.1111/j.1438-8677.2010.00407.x. View

Acosta-Garcia G, Vielle-Calzada J . A classical arabinogalactan protein is essential for the initiation of female gametogenesis in Arabidopsis. Plant Cell. 2004; 16(10):2614-28. PMC: 520959. DOI: 10.1105/tpc.104.024588. View

Rafinska K, Bednarska E . Localisation pattern of homogalacturonan and arabinogalactan proteins in developing ovules of the gymnosperm plant Larix decidua Mill. Sex Plant Reprod. 2010; 24(1):75-87. DOI: 10.1007/s00497-010-0154-8. View

Ma H, Zhao J . Genome-wide identification, classification, and expression analysis of the arabinogalactan protein gene family in rice (Oryza sativa L.). J Exp Bot. 2010; 61(10):2647-68. PMC: 2882264. DOI: 10.1093/jxb/erq104. View

Petersen B, Egelund J, Damager I, Faber K, Jensen J, Yang Z . Assay and heterologous expression in Pichia pastoris of plant cell wall type-II membrane anchored glycosyltransferases. Glycoconj J. 2009; 26(9):1235-46. PMC: 2793385. DOI: 10.1007/s10719-009-9242-0. View

Keegstra K, Talmadge K, Bauer W, Albersheim P . The Structure of Plant Cell Walls: III. A Model of the Walls of Suspension-cultured Sycamore Cells Based on the Interconnections of the Macromolecular Components. Plant Physiol. 1973; 51(1):188-97. PMC: 367377. DOI: 10.1104/pp.51.1.188. View

10.

Estevez J, Kieliszewski M, Khitrov N, Somerville C . Characterization of synthetic hydroxyproline-rich proteoglycans with arabinogalactan protein and extensin motifs in Arabidopsis. Plant Physiol. 2006; 142(2):458-70. PMC: 1586053. DOI: 10.1104/pp.106.084244. View

11.

Tryfona T, Liang H, Kotake T, Kaneko S, Marsh J, Ichinose H . Carbohydrate structural analysis of wheat flour arabinogalactan protein. Carbohydr Res. 2010; 345(18):2648-56. DOI: 10.1016/j.carres.2010.09.018. View

12.

Moller I, Sorensen I, Bernal A, Blaukopf C, Lee K, Obro J . High-throughput mapping of cell-wall polymers within and between plants using novel microarrays. Plant J. 2007; 50(6):1118-28. DOI: 10.1111/j.1365-313X.2007.03114.x. View

13.

Tan L, Varnai P, Lamport D, Yuan C, Xu J, Qiu F . Plant O-hydroxyproline arabinogalactans are composed of repeating trigalactosyl subunits with short bifurcated side chains. J Biol Chem. 2010; 285(32):24575-83. PMC: 2915693. DOI: 10.1074/jbc.M109.100149. View

14.

Schultz C, Rumsewicz M, Johnson K, Jones B, Gaspar Y, Bacic A . Using genomic resources to guide research directions. The arabinogalactan protein gene family as a test case. Plant Physiol. 2002; 129(4):1448-63. PMC: 166734. DOI: 10.1104/pp.003459. View

15.

Irshad M, Canut H, Borderies G, Pont-Lezica R, Jamet E . A new picture of cell wall protein dynamics in elongating cells of Arabidopsis thaliana: confirmed actors and newcomers. BMC Plant Biol. 2008; 8:94. PMC: 2551616. DOI: 10.1186/1471-2229-8-94. View

16.

Shimizu M, Igasaki T, Yamada M, Yuasa K, Hasegawa J, Kato T . Experimental determination of proline hydroxylation and hydroxyproline arabinogalactosylation motifs in secretory proteins. Plant J. 2005; 42(6):877-89. DOI: 10.1111/j.1365-313X.2005.02419.x. View

17.

Choi Y, Kim S, Lee S, Kim S, Yoon G, Kim H . Isolation and promoter analysis of anther-specific genes encoding putative arabinogalactan proteins in Malus x domestica. Plant Cell Rep. 2009; 29(1):15-24. DOI: 10.1007/s00299-009-0794-z. View

18.

Shi H, Kim Y, Guo Y, Stevenson B, Zhu J . The Arabidopsis SOS5 locus encodes a putative cell surface adhesion protein and is required for normal cell expansion. Plant Cell. 2003; 15(1):19-32. PMC: 143448. DOI: 10.1105/tpc.007872. View

19.

Duan J, Zheng Y, Dong Q, Fang J . Structural analysis of a pectic polysaccharide from the leaves of Diospyros kaki. Phytochemistry. 2004; 65(5):609-15. DOI: 10.1016/j.phytochem.2003.12.002. View

20.

Ichinose H, Kuno A, Kotake T, Yoshida M, Sakka K, Hirabayashi J . Characterization of an exo-beta-1,3-galactanase from Clostridium thermocellum. Appl Environ Microbiol. 2006; 72(5):3515-23. PMC: 1472343. DOI: 10.1128/AEM.72.5.3515-3523.2006. View