Predictors of Exposure to Organophosphate Pesticides in Schoolchildren in the Province of Talca, Chile

Overview

Journal Environ Int

Specialties Environmental Health
Toxicology

Date 2012 Jun 27

PMID 22732215

Citations 17

Authors

Maria Teresa Munoz-Quezada

Veronica Iglesias

Boris Lucero

Kyle Steenland

Dana Boyd Barr

Karen Levy

P Barry Ryan

Sergio Alvarado

Carlos Concha

Affiliations

Soon will be listed here.

Abstract

Background: Few data exist in Latin America concerning the association between organophosphate (OP) urinary metabolites and the consumption of fruits and vegetables and other exposure risk variables in schoolchildren.

Methods: We collected samples of urine from 190 Chilean children aged 6-12 years, fruits and vegetables, water and soil from schools and homes, and sociodemographic data through a questionnaire. We measured urinary dialkylphosphate (DAP) OP metabolites and OP pesticide residues in food consumed by these 190 children during two seasons: December 2010 (summer) and May 2011 (fall). We analyzed the relationship between urinary DAP concentrations and pesticide residues in food, home pesticide use, and residential location.

Results: Diethylalkylphosphates (DEAP) and dimethylalkylphosphates (DMAP) were detected in urine in 76% and 27% of the samples, respectively. Factors associated with urinary DEAP included chlorpyrifos in consumed fruits (p<0.0001), urinary creatinine (p<0.0001), rural residence (p=0.02) and age less than 9 years (p=0.004). Factors associated with urinary DMAP included the presence of phosmet residues in fruits (p<0.0001), close proximity to a farm (p=0.002), home fenitrothion use (p=0.009), and season (p<0.0001).

Conclusions: Urinary DAP levels in Chilean school children were high compared to previously reported studies. The presence of chlorpyrifos and phosmet residues in fruits was the major factor predicting urinary DAP metabolite concentrations in children.

Citing Articles

The Assessment of Organophosphate Pesticide Exposure among School Children in Four Regions of Thailand: Analysis of Dialkyl Phosphate Metabolites in Students' Urine and Organophosphate Pesticide Residues in Vegetables for School Lunch.

Wongta A, Sawang N, Tongjai P, Jatiket M, Hongsibsong S Toxics. 2022; 10(8).

PMID: 36006115 PMC: 9416577. DOI: 10.3390/toxics10080434.

Psychometric Validation of a Questionnaire to Assess Perception and Knowledge About Exposure to Pesticides in Rural Schoolchildren of Maule, Chile.

Munoz-Quezada M, Lucero B, Castillo B, Bradman A, Zuniga L, Baumert B Front Psychol. 2021; 12:715477.

PMID: 34630226 PMC: 8492929. DOI: 10.3389/fpsyg.2021.715477.

Assessment of Organophosphate Pesticides Exposure in Men with Idiopathic Abnormal Semen Analysis: A Cross-Sectional Pilot Study.

Manikandan I, Bora S, Adole P, Thyagaraju C, Ganesh R Int J Fertil Steril. 2021; 15(3):219-225.

PMID: 34155869 PMC: 8233921. DOI: 10.22074/IJFS.2020.134650.

Characteristics of Exposure of Reproductive-Age Farmworkers in Chiang Mai Province, Thailand, to Organophosphate and Neonicotinoid Insecticides: A Pilot Study.

Suwannarin N, Prapamontol T, Isobe T, Nishihama Y, Nakayama S Int J Environ Res Public Health. 2020; 17(21).

PMID: 33121069 PMC: 7663695. DOI: 10.3390/ijerph17217871.

Risk perception and behavior in Egyptian adolescent pesticide applicators: an intervention study.

Rohlman D, Davis J, Ismail A, Abdel Rasoul G, Hendy O, Olson J BMC Public Health. 2020; 20(1):679.

PMID: 32404149 PMC: 7222587. DOI: 10.1186/s12889-020-08801-7.

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