High Prevalence of Colonization with Staphylococcus Aureus Clone USA300 at Multiple Body Sites Among Sexually Transmitted Disease Clinic Patients: an Unrecognized Reservoir

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2012 Jun 26

PMID 22728758

Citations 18

Authors

Benjamin A Miko

Anne-Catrin Uhlemann

Amanda Gelman

Caroline J Lee

Cory A Hafer

Sean B Sullivan

Qiuhu Shi

Maureen Miller

Jonathan Zenilman

Franklin D Lowy

Affiliations

Soon will be listed here.

Abstract

Extranasal colonization is increasingly recognized as an important reservoir for Staphylococcus aureus among high-risk populations. We conducted a cross-sectional study of multiple body site colonization among 173 randomly selected STD clinic patients in Baltimore, Maryland. Staphylococcal carriage at extranasal sites, including the oropharynx, groin, rectum, and genitals, was common among study subjects. The USA300 clone was particularly associated with multiple sites of colonization compared with non-USA300 strains (p = .01). Given their high burden of multi-site colonization and confluence of established staphylococcal risk factors, STD clinic patients may represent a community-based reservoir for S. aureus and be well suited for innovative infection control initiatives.

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