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New Insights into the Role of NK Cells in Cancer Immunotherapy

Overview
Journal Oncoimmunology
Specialty Allergy & Immunology
Date 2012 Jun 22
PMID 22720243
Citations 17
Authors
Maria Salagianni
Constantin N Baxevanis
Michael Papamichail
Sonia A Perez
Affiliations
Soon will be listed here.
Abstract

Repetitive infusions of ex vivo expanded NK cells induced antitumor T-cell responses in a metastatic lung cancer mouse model. These were further potentiated by Treg depletion. Thus the combination of NK cell-based immunotherapy with other treatment modalities in the direction of adaptive response enhancement might promote long lasting antitumor immunity.

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